Efficacy of IFN-γ, sCD40L, and Poly(I:C) Treated Bone Marrow-Derived Macrophages in Murine Mammary Carcinoma.

Introduction: Here, we explored methods to generate anti-tumor bone marrow-derived macrophages (BMDM) and how delivery of the BMDM at early tumor sites could impact disease progression.

Methods: BMDM treated with IFN-γ, sCD40L, poly(I:C), and a combination of the three were assessed.

Results: Treatment with sCD40L had no significant impact on the BMDM.