SARS-CoV-2 Transmission Dynamics in Households With Children, Los Angeles, California.

Studies of household transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) focused on households with children are limited. We investigated household secondary attack rate (SAR), transmission dynamics, and contributing factors in households with children. In this prospective case-ascertained study in Los Angeles County, California, all households members were enrolled if ≥1 member tested positive for SARS-CoV-2 by polymerase chain reaction (PCR).

Clinical manifestations of COVID-19 differ by age and obesity status.

Background: Age and obesity status are associated with severe outcomes among hospitalized individuals with COVID-19. It remains unclear whether age and obesity are risk factors for milder COVID-19 illness.

Methods: We prospectively enrolled SARS-CoV-2-exposed individuals.