Pharmaceutical cocrystals are created by combining an active pharmaceutical ingredient with a cocrystal former, resulting in unique crystalline solids.
Two specific cocrystals studied are 2,6-diaminopyridine-piracetam and 2,6-diaminopyridine-theophylline, both characterized using solvent-assisted grinding and analytical techniques like IR spectroscopy and powder X-ray diffraction.
These cocrystals exhibit distinct structural features, including specific hydrogen bonding interactions that lead to unique arrangements, such as one forming a two-dimensional sheet and the other a bidimensional supramolecular array.