Understanding the spectrum of malignant bowel obstructions in gynecologic cancers and the application of the Henry score.

Objective: Malignancy-associated bowel obstruction (MBO) is a potential sequela of advanced gynecologic cancers, adversely impacting both quality of life and prognosis. The Henry score (HS) was developed in a gastrointestinal cancer-predominant population to predict 30-day mortality. We aim to characterize MBO in gynecologic cancers and assess the utility of the HS in this population.

Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms.

Embryonic morphogenesis is powered by dramatic changes in cell shape and arrangement driven by the cytoskeleton and its connections to adherens junctions. This requires robust linkage allowing morphogenesis without disrupting tissue integrity. The small GTPase Rap1 is a key regulator of cell adhesion, controlling both cadherin-mediated and integrin-mediated processes.

Stabilization of T4 bacteriophage at acidic and basic pH by adsorption on paper.

Bacteriophages find applications in agriculture, medicine, and food safety. Many of these applications can expose bacteriophages to stresses that inactivate them including acidic and basic pH. Bacteriophages can be stabilized against these stresses by materials including paper, a common material in packaging and consumer products.

Low-Cost Sensor System Design for In-Home Physical Activity Tracking.

An aging and more sedentary population requires interventions aimed at monitoring physical activity, particularly within the home. This research uses simulation, optimization, and regression analyses to assess the feasibility of using a small number of sensors to track movement and infer physical activity levels of older adults. Based on activity data from the American Time Use Survey and assisted living apartment layouts, we determined that using three to four doorway sensors can be used to effectively capture a sufficient amount of movements in order to estimate activity.

Trajectories of perceived adult and peer discrimination among Black, Latino, and Asian American adolescents: patterns and psychological correlates.

This article presents results from a 3-year longitudinal study of the growth patterns and correlates of perceived discrimination by adults and by peers among Black, Latino, and Asian American high school students. Results revealed a linear increase over time in levels of perceived discrimination by adults, whereas perceptions of discrimination by peers remained stable over time. Asian American and non-Puerto Rican Latino adolescents (primarily Dominican) reported higher levels of peer and/or adult discrimination than did Puerto Rican youth, whereas Black adolescents reported a steeper increase over time in levels of perceived discrimination by peers and by adults than did Puerto Rican adolescents.