Early goal-directed therapy for severe sepsis and septic shock: A living systematic review.

Unlabelled: Studies and meta-analyses conflict regarding the use of early goal-directed therapy (EGDT) for septic shock. We sought to clarify the conflict by performing a living systematic review and meta-regression.

Methods: We performed a meta-analysis and explored heterogeneity with meta-regression.

Swollen right hand and forearm · minor trauma to hand · previous diagnosis of cellulitis · Dx?

A 63-year-old woman with a history of hyperlipidemia presented to our hospital with a swollen right hand. The patient noted that she had closed her hand in a car door one week earlier, causing minor trauma to the right third metacarpophalangeal joint. Shortly after injuring her hand, she'd sought care at an outpatient facility, where she was given a diagnosis of cellulitis and a prescription for an oral antibiotic.