A Comparison of Trabeculectomy Surgery Outcomes With Mitomycin-C Applied by Intra-Tenon Injection Versus Sponge.

Purpose: To compare the outcomes of mitomycin-C (MMC) delivered by intra-Tenon injection vs sponge application during trabeculectomy surgery.

Methods: We retrospectively reviewed 566 patients with primary and secondary glaucoma diagnoses who received trabeculectomy surgery with MMC in an academic medical center. Exclusion criteria were age less than 18 years, no light perception vision, combined surgery, previous glaucoma incisional surgery, intraoperative 5-fluorouracil, or follow-up <1 month.

Immunoproteomic analysis of potential serum biomarker candidates in human glaucoma.

Purpose: Evidence supporting the immune system involvement in glaucoma includes increased titers of serum antibodies to retina and optic nerve proteins, although their pathogenic importance remains unclear. This study using an antibody-based proteomics approach aimed to identify disease-related antigens as candidate biomarkers of glaucoma.

Methods: Serum samples were collected from 111 patients with primary open-angle glaucoma and an age-matched control group of 49 healthy subjects without glaucoma.

Rosai-dorfman disease diagnosed because of bilateral choroidal masses.

Purpose: To describe a case of bilateral choroidal masses leading to the diagnosis of Rosai-Dorfman disease.

Method: Case report. Color photographs, fluorescein angiography, autofluorescence, indocyanine green angiography, and high-definition optical coherence tomography imaging of both eyes and computed tomography and biopsy of pelvis mass were performed.

Multifocal choroiditis secondary to the reactivation of epstein-barr virus.

Purpose: To describe a case of multifocal choroiditis associated with Epstein-Barr virus reactivation in a patient who had previously had documented infectious mononucleosis.

Methods: Color photos, fluorescein angiography, autofluorescence, indocyanine green angiography, and high-definition optical coherence tomography imaging was performed. A 39-year-old woman presented with a central scotoma in her left eye.

Dorzolamide as an Effective Topical Therapy for Glaucoma in a Case of Nanophthalmos.

To report a case of nanophthalmos in which the intraocular pressure (IOP) off medication was 45 mm Hg and on dorzolamide hydrochloride once daily was 15 mm Hg for many years. No other medication affected the IOP. A chart review of a patient with nanophthalmos and glaucoma.

Subconjunctival sodium hyaluronate 2.3% in trabeculectomy: a prospective randomized clinical trial.

Purpose: To investigate the efficacy of subconjunctival sodium hyaluronate 2.3% in increasing the success rate of glaucoma filtering surgery and promoting filtering blebs with characteristics presumed to predict better success.

Design: Randomized controlled clinical trial.