Background: Antimicrobial resistance killed 1.27 million people in 2019, so urgent actions are desperately needed. Antimicrobial stewardship programmes (ASPs) are essential to optimize antimicrobial use.
View Article and Find Full Text PDFBackground: Tigecycline is the first member of the glycylcyclines. Both the FDA (2010 and 2013) and the EMA (2011) issued safety warnings describing an increased mortality risk associated with tigecycline compared with other antibiotics treating severe infections. One of the best strategies to optimize antimicrobial therapies is through the establishment of antimicrobial stewardship programmes (ASPs) in hospitals.
View Article and Find Full Text PDFBackground: Cutaneous adverse drug reactions (CADRs) due to bisphosphonates (BPs) have been scarcely described in the literature.
Objective: To discuss the diagnostic value and limitations of cutaneous provocation tests with BPs.
Methods: A descriptive case series study with a control group of CADRs due to BPs studied using patch testing from 2005 to 2010 is presented.
Objective: Despite the increasing ethnic diversity, there are few studies of its influence on the pharmacokinetics of amikacin. The objective of this study was to compare the pharmacokinetics of amikacin in different populations: Asian, Hispanic, North Africans and Caucasian.
Methods: A retrospective observational study was performed in a tertiary teaching hospital during eight years.