Publications by authors named "Melis Coremen"
Sodium valproate- a salt of valproic acid (VPA), is an anticonvulsant used in the treatment of epilepsy and a range of psychiatric conditions that include panic attacks, anxiety, post-traumatic stress, migraine and bipolar disorder etc. VPA can cause direct damage to many tissues due to accumulation of toxic metabolites. Nowadays, phytochemicals are amongst the best options for the treatment of diseases.
View Article and Find Full Text PDFProstate damage can occur in men due to age and genetic factors, especially when exposed to external factors. Radiation (RAD) is a prominent factor leading to oxidative stress and potential prostate damage. Additionally, chloroquine (CQ), used in malaria treatment, can induce oxidative stress in a dose-dependent manner.
View Article and Find Full Text PDFValproic acid is an effective treatment for generalized seizure and related neurological defects. Despite its efficacy and acceptability, its use is associated with adverse drug effects. leaves are rich in phytochemical and nutritional components.
View Article and Find Full Text PDFArticle Synopsis
- - The study examined the toxicity of various pesticides on rat liver and investigated whether lupeol could mitigate this toxicity.
- - Male Wistar rats were divided into groups receiving either control substances or different pesticides, with some groups also receiving lupeol for comparison over ten days.
- - Results showed severe liver damage and oxidative stress from pesticides, while lupeol appeared to have a protective effect against this damage.