Publications by authors named "Melinda M Rottas"

Article Synopsis
  • The study addresses the importance of diversity in clinical trials (CTs) to improve health equity and ensure that findings are applicable to diverse populations.
  • An advisory board of experts was formed to create a framework for setting enrollment goals that incorporates data from various sources, including the US Census and real-world data.
  • The resulting framework aims to establish transparent, reproducible enrollment goals while highlighting ethical considerations and addressing limitations related to underrepresented groups in medical research.
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A novel alpha 7 nAChR agonist, 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (24, CP-810,123), has been identified as a potential treatment for cognitive deficits associated with psychiatric or neurological conditions including schizophrenia and Alzheimer's disease.

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