Publications by authors named "Melinda Harrison"

The professional identity of scientists has historically been cultivated to value research over teaching, which can undermine initiatives that aim to reform science education. Course-Based Research Experiences (CRE) and the inclusive Research and Education Communities (iREC) are two successful and impactful reform efforts that integrate research and teaching. The aim of this study is to explicate the professional identity of instructors who implement a CRE within an established iREC and to explore how this identity contributes to the success of these programs.

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Seven bacteriophages were isolated from soil in Pennsylvania and Wisconsin using the host . These bacteriophages range in the number of predicted genes encoded, from 25 to 91, and are distributed across actinobacteriophage clusters EB, EC, EE, and EK.

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phage APunk was isolated from soil collected in Grand Rapids (MI, USA) using Gordonia terrae 3612. The genome of APunk is 59,154 bp long, has a 67.7% GC content, and contains 32 protein-coding genes.

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phage Scuttle was isolated by enrichment from a dry soil sample (collected in Upper Darby, Pennsylvania) on host sp. ATCC 21022. The genome of this phage is 43,729 bp long, has a GC content of 61.

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Eight siphoviral phages isolated from various soil types and locations in southwestern Pennsylvania using sp. strain ATCC 21022 were sequenced. The phages all have relatively small genomes, with each genome containing 15,556 bp.

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Article Synopsis
  • Researchers sequenced the complete genomes of 44 phages that infect the bacterial strain ATCC 21022.
  • The phages have double-stranded DNA genomes, varying in size from 15,680 to 70,707 base pairs, and their G+C contents range from 45.1% to 68.5%.
  • The study includes phages with three different tail types, classified into specific families.
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Article Synopsis
  • Caterpillar, Nightmare, and Teacup are three types of siphoviral phages discovered in enriched soil associated with a specific bacterial strain.
  • Their genomes are relatively large, measuring 58 kilobase pairs (kbp) with a balanced G+C content of 50%.
  • Genetic analysis suggests they contain between 86 to 92 protein-coding genes, many of which are small proteins thought to have transmembrane domains.
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Article Synopsis
  • Twelve siphoviral phages were isolated using the ATCC 21022 strain.
  • Their genome sizes are small, ranging between 15,319 and 15,556 base pairs.
  • All 12 phages are closely related to existing phages in cluster AN.
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We report here the genome sequences of six newly isolated bacteriophages infecting sp. ATCC 21022. All six have myoviral morphologies and have double-stranded DNA genomes with circularly permuted ends.

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The vast bacteriophage population harbors an immense reservoir of genetic information. Almost 2000 phage genomes have been sequenced from phages infecting hosts in the phylum Actinobacteria, and analysis of these genomes reveals substantial diversity, pervasive mosaicism, and novel mechanisms for phage replication and lysogeny. Here, we describe the isolation and genomic characterization of 46 phages from environmental samples at various geographic locations in the U.

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Mycobacteriophages represent a genetically diverse group of viruses that infect mycobacterial hosts. Although more than 80 genomes have been sequenced, these still poorly represent the likely diversity of the broader population of phages that can infect the host, Mycobacterium smegmatis mc(2)155. We describe here a newly discovered phage, Marvin, which is a singleton phage, having no previously identified close relatives.

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Our study, focused on classroom-based research at the introductory level and using the Phage Genomics course as the model, shows evidence that first-year students doing research learn the process of science as well as how scientists practice science. A preliminary but notable outcome of our work, which is based on a small sample, is the change in student interest in considering different career choices such as graduate education and science in general. This is particularly notable, as previous research has described research internships as clarifying or confirming rather than changing undergraduates' decisions to pursue graduate education.

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