Publications by authors named "Melina Sadighara"

Article Synopsis
  • * The review highlights that the Maillard reaction plays a key role in acrylamide formation, with suppression of this reaction yielding the most significant reduction effects, often over 90% in some studies.
  • * Antioxidants have also shown effectiveness in reducing acrylamide levels by 50-90%, with tropical fruits and bamboo leaves proving to be particularly beneficial in biscuit formulations.
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Statins are widely used in patients with hyperlipidemia and whom with high risk of cardiovascular diseases. Unfortunately, statins also exert some adverse effects on the liver and pancreas and enhance the risk of type 2 diabetes mellitus. The objective of the present research was to investigate the protective effects of coenzyme Q (Co-Q) and L-carnitine (LC) on statins induced toxicity on pancreatic mitochondria .

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Statins (including atorvastatin) are a widely used class of drugs, and like all medications, they have a potential for adverse effects. Recently, it has been shown that statins also exert side effects on the pancreas. In vitro studies have suggested that this class of drugs induced a reduction in insulin secretion.

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