Comparative Analysis of Transcriptome Profiles in Patients with Thromboangiitis Obliterans.

Background: Thromboangiitis obliterans (TAO) causes vascular insufficiency due to chronic inflammation and abrupt thrombosis of the medium and small arteries of the extremities. In our study, we aimed to determine biomarkers for the diagnosis of TAO by evaluating 15 male TAO patients with Shinoya diagnostic criteria and 5 healthy controls who did not have TAO-related symptoms in their family histories.

Methods: The Clariom D Affymetrix platform was used to conduct microarray analysis on total RNA extracted from whole blood.

Brief Review of Right Aortic Arch with Aberrant Left Subclavian Artery.

Development anomalies of the aortic arch and its major branches are rare congenital cardiovascular disorders. In this article, we present aberrant left subclavian artery associated with right aortic arch.