Publications by authors named "Melike Cengiz"

Percutaneous dilatational tracheostomy (PDT) is the most commonly performed minimally invasive intensive care unit procedure worldwide. This study evaluated the percentage of consistency between the entry site observed with fiberoptic bronchoscopy (FOB) and the prediction for the PDT level based on pre-procedural ultrasonography (USG) in PDT procedures performed using the forceps dilatation method. The effect of morphological features on intervention sites was also investigated.

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Background: Vaccines against coronavirus disease-19 (COVID-19) have been effective in preventing symptomatic diseases, hospitalizations, and intensive care unit (ICU) admissions. However, data regarding the effectiveness of COVID-19 vaccines in reducing mortality among critically ill patients with COVID-19 remains unclear.

Aims: To determine the vaccination status and investigate the impact of the COVID-19 vaccine on the 28-day mortality in critically ill patients with COVID-19.

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Background: Liver transplantation is a life-saving treatment in end-stage liver failure. Hemorheological features as blood fluidity and red blood cell aggregation may alter effective tissue perfusion, graft function and hemodynamic variables.

Objective: The aim of the study is to investigate effect of albumin infusion on red blood cell deformability and aggregation, blood viscosity and hemodynamics in liver transplant patients.

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Objective: To describe surgical procedures, previous failed pregnancies, methods for overcoming pregnancy failure and, most importantly, birth of a healthy infant, in a uterus transplantation from a deceased donor.

Background: Majority of uterus transplants have involved live donors, but several advantages make deceased donor transplantation a practicable option, principally by eliminating surgical risks to the live donor.

Methods: Uterus transplantation from a deceased donor was performed in September 2011 in Turkey.

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In this double-blind, controlled, cross-sectional study, we compared structural changes in the cervical vertebrae of patients with nonradiographic axial spondyloarthropathy (nr-axSpA), patients with ankylosing spondylitis (AS), and a control group. We used the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) to determine whether the involvement of the cervical spine occurs earlier and is more severe than that of the lumbar spine in axial spondyloarthropathy (axSpA). A statistically significant difference was found in the total mSASSS between the AS and nr-axSpA groups (p = 0.

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Objective: Despite advances in immunosuppressive drugs, postoperative care, and surgical techniques, bacterial infections remain the most important cause of morbidity and mortality in liver transplant patients. The aim of this study is to evaluate the influence of culture results taken on the first day of admission to intensive care unit on mortality, graft rejection, mechanical ventilation duration, and length of intensive care unit stay. Our study has clinical importance because it is the first study evaluating the cultures obtained on the first day of intensive care unit stays in liver transplant patients.

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Objectives: The aim of this study is to investigate the factors affecting cost in patients with severe community-acquired pneumonia (CAP) who were admitted to the intensive care unit (ICU).

Materials And Methods: This retrospective cohort study was conducted between January 2013 and December 2016. A total of 291 sequential patients with severe CAP were included in the study.

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Objective: Solid organ transplantation is a rescue therapy, whereas face transplantation, as well as other composite tissue allotransplantations, offers treatment options to enhance the quality of life. Difficult airway, severe haemorrhage and prolonged operative length are among the frequently encountered complications of anaesthetic management in patients with a history of multiple reconstructive surgeries.

Methods: Five face allotransplants that were performed in our institute, arising from four full and one partial face transplantations, were reviewed.

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Article Synopsis
  • - The study aimed to gather data on the characteristics of intensive care units (ICUs) in Turkey through a nationwide point prevalence survey conducted by the Turkish Thoracic Society.
  • - Data from 67 ICUs revealed that 76.1% operated under a closed system, with 35.8% classified as Level of Care (LOC) 2 and 64.2% as LOC 3, indicating a range of critical care capacity.
  • - The findings highlighted a significant need for more specialized physicians and nurses in ICUs, particularly during nighttime, although the percentage of certified ICU nurses was seen as relatively adequate, with aspirations for full certification.
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  • Community-acquired pneumonia (CAP) significantly increases the risk of cardiovascular complications, particularly in severe cases, though there is limited information on this topic.
  • This study analyzed data from 373 patients with severe CAP to assess the prevalence, characteristics, and risk factors associated with acute cardiac events and their impact on mortality.
  • Results indicated that 15% of patients experienced cardiac events, which were linked to older age, more severe illness, and higher in-hospital mortality rates, highlighting the need for awareness and monitoring in these patients.
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Background: The aim of this report is to present our long-term experiences with a series of 5 face-transplanted patients in terms of surgical aspects and postoperative outcomes, and to describe possible salvage strategies in case of difficulties.

Methods: Five patients, 4 receiving full-face transplantation and 1 undergoing partial transplantation at our institution were included. The patients were aged between 19 and 54 years.

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This study investigated the effects of magnesium on blood rheological properties and blood pressure in nitric oxide synthase (NOS) inhibition-induced hypertension model. Hypertension was induced by oral administration of the nonselective NOS inhibitor N-nitro-L-arginine methyl ester (L-NAME, 25 mg/kg/day) for 6 weeks and systolic blood pressure was measured by the tail-cuff method. The groups receiving magnesium supplementation were fed with rat chow containing 0.

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Aim: To examine the use of prognostic factors such as age, Glasgow Coma Scale (GCS) score, pupil reactivity and computerized tomography (CT) findings for predicting the prognosis of severe traumatic brain injury (TBI) patients in Turkey.

Material And Methods: We retrospectively evaluated TBI patients who were accepted to Akdeniz University Intensive Care Unit between 1 January 2007 and 31 December 2009. Patient data were collected from the hospital information system.

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This study investigated the effect of magnesium on the vascular reactivity of conduit and resistance arteries in a nitric oxide synthase inhibition-induced hypertension model. The aorta and third-order branches of the mesenteric artery were dissected from normotensive control and hypertensive rats, and their constriction and dilation responses in physiological saline solution containing normal (1.2 mM) or high (4.

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We describe a rare case of fatal disseminated tuberculous peritonitis in a young woman with rapid progressive clinical course following spontaneous abortion of 20-week gestation. Clinical and laboratory findings were initially unremarkable. She underwent diagnostic laparoscopy which revealed numerous tiny implants on the peritoneum and viscera.

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The aim of this study is to develop and evaluate a web-based clinical decision support system (CDSS) containing clinical guidelines and protocols that will support intensive care unit (ICU) providers in making decisions more effectively and quickly. First, a survey was carried out with 38 physicians in order to determine their preferences, needs and concerns regarding decision support tools. After the survey, guidelines were prepared by a group of specialists in ICU, and a medical informatician converted the guidelines into algorithm forms.

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A study was carried out to assess treatment success and the overall costs of patients with ventilator-associated pneumonia (VAP). In a prospective case control study, data were collected from 25 intensive care unit (ICU) beds. A total of 162 ICU patients who required mechanical ventilation were assessed.

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Article Synopsis
  • The International Society for Clinical Hemorheology compared three RBC aggregation measurement instruments: LORCA, Myrenne Aggregometer, and RheoScan-A, focusing on their parameters and performance.
  • Key findings included low intra-assay variation for most instruments, with notable differences in their ability to detect changes in RBC aggregation under various conditions, such as plasma dilution and dextran treatment.
  • The study concluded that while each instrument has good precision for detecting reductions in RBC aggregation, the RheoScan-A may miss significant increases in aggregation, indicating a need for further research on their effective ranges for measuring RBC aggregation.
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Measurement of red blood cell (RBC) deformability by ektacytometry yields a set of elongation indexes (EI) measured at various shear stresses (SS) presented as SS-EI curves, or tabulated data. These are useful for detailed analysis, but may not be appropriate when a simple comparison of a global parameter between groups is required. Based on the characteristic shape of SS-EI curves, two approaches have been proposed to calculate the maximal RBC elongation index (EI(max)) and the shear stress required for one-half of this maximal deformation (SS(1/2)): (i) linear Lineweaver-Burke (LB) model; (ii) Streekstra-Bronkhorst (SB) model.

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Background: This study aims to determine the frequency of maxillary sinusitis in the patients with traumatic head injury and nostrils free of any foreign body. In addition, the sensitivity and specificity of ultrasonography (US) for the detection of the presence of fluid in maxillary sinuses were evaluated.

Patients And Methods: Forty patients with severe traumatic head injury were included in the study.

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In December 2008, the International Society for Clinical Hemorheology organized a workshop to evaluate and compare three ektacytometer instruments for measuring deformability of red blood cells (RBC): LORCA (Laser-assisted Optical Rotational Cell Analyzer, RR Mechatronics, Hoorn, The Netherlands), Rheodyn SSD (Myrenne GmbH, Roetgen, Germany) and RheoScan-D (RheoMeditech, Seoul, Korea). Intra-assay reproducibility and biological variation were determined using normal RBC, and cells with reduced deformability (i.e.

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Article Synopsis
  • Venous blood sampling typically uses a tourniquet to locate veins, but its effects on lab results are not well understood, leading to a lack of guidelines on usage.
  • A study compared various blood parameters before and after tourniquet removal in healthy subjects, revealing no significant changes in blood gases, hematological data, or electrolytes, but notable effects on erythrocyte deformability and aggregation.
  • The results suggest that while routine blood tests remain reliable post-tourniquet, measures of blood flow properties can be impacted, indicating a need for standardized procedures if tourniquets are necessary.
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Blood samples used in hemorheological studies may be stored for a period of time, the effects of storage have yet to be fully explored. This study evaluated the effects of storage temperature (i.e.

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Introduction: Percutaneous tracheostomy is a widely used and accepted method for long-term mechanical ventilation and airway protection. Neurocritically ill patients sometimes require repeat tracheostomy, which is traditionally considered a relative contraindication for percutaneous procedure. The aim of this study was to determine the safety of repeat percutaneous tracheostomy in neurocritically ill patients with a history of previous tracheostomy.

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