Publications by authors named "Melih Kaya"
Oxytocin shortens spreading depolarization-induced periorbital allodynia.
J Headache Pain
September 2024
Article Synopsis
- The study investigates the role of cortical spreading depolarization (SD) in triggering migraine-related pain by focusing on a specific brain region, the paraventricular nucleus (PVN), and its connection to oxytocin signaling.* -
- Using a genetically modified mouse model, researchers found that opto-SD significantly increased markers of neuronal activity in the PVN, indicating that this area is activated during migraine-like pain responses.* -
- Treatment with an oxytocin receptor antagonist reduced pain behavior induced by opto-SD, suggesting that oxytocin plays a role in modulating trigeminal pain linked to migraines.*
This study evaluated the effects of 9% etidronic acid (HEBP) and 17% ethylenediaminetetraacetic acid (EDTA) used either with conventional syringe irrigation (CSI) or passive ultrasonic irrigation (PUI) on the fracture resistance of roots with different dentine thickness. The root canals of 120 extracted teeth were widened, leaving dentinal walls with different thicknesses of either 0.75 mm, 1.
View Article and Find Full Text PDFHerein, we report a rational design in preparation of natural indicator incorporated media used as a rapid, selective, sensitive and economic colorimetric biosensor for detection of Methicillin-resistant Staphylococcus aureus (MRSA). Anthocyanins obtained from red cabbage (Brassica oleracea) extract (RCE) are major components and acted as pH responsive indicators in the RCE media. The RCE media was tested for eight gram-positive, four gram-negative bacterial and one model fungal pathogens.
View Article and Find Full Text PDFEffect of Root Canal Disinfection with a Diode Laser on Postoperative Pain After Endodontic Retreatment.
Photobiomodul Photomed Laser Surg
February 2019
The aim of this randomized clinical trial was to evaluate the influence of root canal disinfection with a 940-nm diode laser on the intensity of pain after endodontic retreatment. Microorganisms are the most common causes of tooth pain. Therefore, clinical studies are needed to explore the effect of disinfection techniques on postoperative pain.
View Article and Find Full Text PDFObjective: To evaluate the safety of sodium hypochlorite (NaOCl) irrigation using three different techniques during the final rinse in overinstrumented root canals.
Background Data: The effect of irrigant activation on irrigant extrusion from overinstrumented root canals is still unclear.
Methods: A total of 30 single-rooted teeth were decoronated.