Publications by authors named "Mele E"

The Internet of Things (IoT) is set to play a significant role in the future development of smart cities, which are designed to be environmentally friendly. However, the proliferation of these devices, along with their frequent replacements and the energy required to power them, contributes to a significant environmental footprint. In this paper we provide scientific evidences on the advantages of using an energy design pattern named 'Batch Operations' (BO) to optimize energy consumption on mobile devices.

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Studies of moiré systems have explained the effect of superlattice modulations on their properties, demonstrating new correlated phases. However, most experimental studies have focused on a few layers in two-dimensional systems. Extending twistronics to three dimensions, in which the twist extends into the third dimension, remains underexplored because of the challenges associated with the manual stacking of layers.

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The XENONnT dark matter experiment.

Eur Phys J C Part Fields

August 2024

The multi-staged XENON program at INFN Laboratori Nazionali del Gran Sasso aims to detect dark matter with two-phase liquid xenon time projection chambers of increasing size and sensitivity. The XENONnT experiment is the latest detector in the program, planned to be an upgrade of its predecessor XENON1T. It features an active target of 5.

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  • Heart failure (HF) is a significant global health issue, especially for the aging population; this study investigates the drug sacubitril/valsartan's effects on aging-related HF with preserved ejection fraction (HFpEF) in rats.
  • After 12 weeks of treatment, both sacubitril/valsartan and valsartan showed improvements in cardiac hypertrophy, evidenced by reduced heart muscle thickness, but neither treatment effectively reduced myocardial fibrosis or corrected diastolic dysfunction.
  • The study indicates that while the treatments positively impacted heart muscle size and activated cardioprotective signaling pathways, challenges like inflammation and oxidative stress remained unaddressed, leaving diastolic dysfunction and fibrosis in aging hearts.
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  • Heart failure and cognitive impairment are significant public health issues, especially as the global population ages, with strong links to age and multiple health issues.
  • Type 2 diabetes increases risks for both heart and brain health, promoting conditions like heart failure and cognitive decline due to its metabolic complications.
  • New anti-diabetic medications, such as GLP-1R agonists and SGLT2 inhibitors, show promise in reducing the risk of cardiovascular and neurological issues beyond just controlling blood sugar, but further research is needed to fully understand their mechanisms.
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Background: Acute urinary retention in children is uncommon and can be related to several causes. The role of abdominal ultrasound and catheterization is controversial. We aimed to identify the most common causes of acute urinary retention in children, focusing, particularly on the role of bladder catheterization and the diagnostic value of acute ultrasound.

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Essential oils have been identified as effective natural compounds to prevent bacterial infections and thus are widely proposed as bioactive agents for biomedical applications. Across the literature, various essential oils have been incorporated into electrospun fibres to produce materials with, among others, antibacterial, anti-inflammatory and antioxidant activity. However, limited research has been conducted so far on the effect of these chemical products on the physical characteristics of the resulting composite fibres for extended periods of time.

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  • - This study evaluated how voiding cystourethrography (VCUG) affects outcomes for patients with duplex system ureterocele (DSU) who underwent endoscopic decompression (ED), involving 75 patients divided into three groups based on their VCUG results.
  • - The results indicated that patients with preoperative vesicoureteral reflux (VUR) had a significantly higher secondary surgery (SS) rate (82%) compared to those without VUR (32%) and those who didn't have a VCUG (25%).
  • - The findings suggest that while patients without VUR and those without a VCUG had similar outcomes, ongoing monitoring through VCUG could be useful for symptomatic patients after ED, and pre
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To review our experience with >100 patients with primary obstructive megaureter (POM) undergoing endoscopic balloon dilatation (EBD) and a follow-up of up to 12 years and determine potential risk factors for failure. Our hypothesis is that EBD allows for long-term treatment in >80% of patients, and its effectiveness decreases in more severe cases. This is a retrospective study of 123 consecutive patients (131 ureters) undergoing EBD from 2009 to 2021.

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Surface polaritons have proven to be uniquely capable of controlling light-matter interactions. Here we explore surface magnon polaritons in low-loss ferrimagnetic semiconductors, with a focus on their topological phases. We propose several surface magnon polariton devices, including microwave resonators that can strongly enhance magnetic fields and low-loss interconnects joining waveguides with vastly different impedances.

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  • Doxorubicin (DOX), a cancer treatment, causes cardiotoxicity, with early signs showing as diastolic dysfunction and fibrosis.
  • Researchers found that cardiac fibroblasts (CFs) become activated soon after DOX treatment, leading to increased metabolic activity and a shift towards glycolytic energy production.
  • The changes in CFs are linked to myofibroblast differentiation and pro-fibrotic signaling, suggesting that targeting these early CF responses could help mitigate the heart damage caused by anthracycline drugs like DOX.
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Artificial crystals such as moiré superlattices can have a real-space periodicity much larger than the underlying atomic scale. This facilitates the presence of Bloch oscillations in the presence of a static electric field. We demonstrate that the optical response of such a system, when dressed with a static field, becomes resonant at the frequencies of Bloch oscillations, which are in the terahertz regime when the lattice constant is of the order of 10 nm.

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Purpose: To compare vacuum-assisted percutaneous nephrolithotomy (VAmini-PCNL) with retrograde intra-renal surgery (RIRS) for the treatment of renal stones measuring 2-3 cm in diameter.

Material And Methods: This retrospective study included children receiving treatment for pyelocalyceal stones of 2-3 cm in diameter from November 2018 to September 2022. Consecutive patients undergoing VAmini-PCNL after 2020 were compared with a historically matched group undergoing RIRS.

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  • The study investigates the interaction between the endocannabinoid system (ECS) and the kisspeptin system (KS) in controlling male reproduction through the hypothalamus-pituitary-gonadal (HPG) axis in adolescent male rats.
  • Male rats were administered kisspeptin-10 and anandamide, with assessments made on hormone levels, gene expression, and localization of specific neurons to explore the effects of these treatments.
  • The results showed that kisspeptin-10 influenced the expression of proteins related to KS, while anandamide had distinct effects on both KS and ECS, highlighting their complex interaction and influence on reproductive development.
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In two-dimensional artificial crystals with large real-space periodicity, the nonlinear current response to a large applied electric field can feature a strong angular dependence, which encodes information about the band dispersion and Berry curvature of isolated electronic Bloch minibands. Within the relaxation-time approximation, we obtain analytic expressions up to infinite order in the driving field for the current in a band-projected theory with time-reversal and trigonal symmetry. For a fixed field strength, the dependence of the current on the direction of the applied field is given by rose curves whose petal structure is symmetry constrained and is obtained from an expansion in real-space translation vectors.

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The strongly correlated charge density wave (CDW) phase of 1T-TiSe is of interest to verify the claims of a chiral order parameter. Characterization of the symmetries of 1T-TiSe is critical to understand the origin of its intriguing properties. Here we use very low-power, continuous wave laser excitation to probe the symmetries of 1T-TiSe by using the circular photogalvanic effect.

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Crossed Testicular Ectopia (CTE) or transverse testicular ectopia is an anecdotic urogenital anomaly in which both testes are located on the same side, generally associated with a patent processus vaginalis (PPV). The condition can be detected by ultrasound. Nevertheless, the diagnosis is often missed preoperatively and CTE is recognized intraoperatively.

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Two-dimensional van der Waals heterostructures can be engineered into artificial superlattices that host flat bands with significant Berry curvature and provide a favorable environment for the emergence of novel electron dynamics. In particular, the Berry curvature can induce an oscillating trajectory of an electron wave packet transverse to an applied static electric field. Though analogous to Bloch oscillations, this novel oscillatory behavior is driven entirely by quantum geometry in momentum space instead of band dispersion.

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The COVID-19 pandemic enhanced social media communications at a time individuals were unable to leave their homes due to the lockdown measures. A lack of research has been identified on how destination marketing organizations use social media during global health crises. Addressing this gap, the present research uses a mixed-method approach to examine the use of Instagram by Milan and Paris' Destination Marketing Organizations before and during COVID-19 and user engagement with it.

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Background: Management of Pyelo-ureteral Junction Obstruction (PUJO) in poorly functioning kidneys in pediatric patients is still controversial, particularly regarding the role of conservative treatment.

Aim: To evaluate and present the outcomes of internal diversion and follow-up results of a small series of pediatric patients with UPJO in poorly functioning kidneys.

Study Design: Retrospective review of 17 consecutive patients with unilateral PUJO in kidneys with Differential Renal Function (DRF) <20% undergoing temporary internal urinary diversion between 2009 and 2021 at a single tertiary center.

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Integrated phononics plays an important role in both fundamental physics and technology. Despite great efforts, it remains a challenge to break time-reversal symmetry to achieve topological phases and non-reciprocal devices. Piezomagnetic materials offer an intriguing opportunity as they break time-reversal symmetry intrinsically, without the need for an external magnetic field or an active driving field.

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Payment apps and digital wallets are powerful tools used to exchange e-money via the internet. However, with the progressive disappearance of cash, there is a need for the digital equivalent of physical banknotes to guarantee the same level of anonymity of private payments. Few efforts to solve the double-spending problem exist in P2P payments (i.

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Systems with strong light-matter interaction open up new avenues for studying topological phases of matter. Examples include exciton polaritons, mixed light-matter quasiparticles, where the topology of the polaritonic band structure arises from the collective coupling between matter wave and optical fields strongly confined in periodic dielectric structures. Distinct from light-matter interaction in a uniform environment, the spatially varying nature of the optical fields leads to a fundamental modification of the well-known optical selection rules, which were derived under the plane wave approximation.

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Phytochemicals and naturally derived compounds, such as plant extracts and bee products, are regarded as complementary and alternative medicines for the treatment of skin wounds, due to their antibacterial, anti-inflammatory, and antioxidant properties. In recent years, it has been shown that dressings impregnated with honey (particularly Manuka honey) are effective for the topical treatment of wounds and burns, and some of them are currently used in clinics. This has stimulated the development of more advanced dressings based on polymeric nanofibres that can release honey and other bee products (like propolis) to promote wound healing.

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  • Cardiorenal syndrome involves heart and kidney issues that often arise from shared risk factors like hypertension and diabetes.
  • A study on dapagliflozin, a sodium-glucose cotransporter 2 inhibitor, showed it can improve kidney function and reduce markers of renal damage in a non-diabetic model of cardiorenal disease.
  • The drug worked by decreasing inflammation, oxidative stress, and modifying the renin-angiotensin-aldosterone system, suggesting it offers protective benefits for renal health.
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