Traumatic obturator dislocation of the hip associated with ipsilateral subtrochanteric femur fracture in a young adult: a case report.

Introduction: Traumatic obturator-type anterior dislocation of the hip with an ipsilateral subtrochanteric fracture is rarely encountered in clinical practice. This case presentation described a trauma patient with such a rare scenario.

Case Report: This paper reports a case of a 20-year-old Amhara ethnic male patient who had a traumatic anterior dislocation of the hip associated with an ipsilateral subtrochanteric femur fracture after a truck rolled over.

Compliance and associated factors of personal protective equipment among sanitary workers in selected public hospitals, Eastern Ethiopia: A cross-sectional study design.

Background: Adherence to the proper use of protective personal equipment (PPE) in health care facilities including public hospitals is challenging among sanitation workers(SWs) across the world in general and in developing countries in particular. Despite the emphasis inline up on various policies and guidelines for PPE use implementation, inconsistent use of PPE, disobedience to PPE regulations, negligence, ignorance, discomfort, and lacking infection prevention and control (IPC) practice have been identified as main associated factors. All these and other factors contributing for the non-compliance of PPE practice among SWs within the hospitals in nations with limited resources such as Ethiopia, as well as study regions.

Population travel increases the risk of Plasmodium falciparum infection in the highland population of Gardula Zone, South Ethiopia: A longitudinal study.

Population movement influences malaria epidemiology and can be a threat to malaria control and elimination. In Ethiopia, highland dwellers often travel to lowland areas where malaria is endemic. The current study aimed to assess the incidence of malaria and risk factors among dwellers in two highland villages of the former Dirashe District (now Gardula Zone), South Ethiopia.

Cervical Cancer Screening Utilization and Barriers to Uptake in Ethiopia: .

Background: Cervical cancer (CCa) is the second most common type of cancer and a leading cause of death among adult women in Ethiopia. However, at the moment, there is a lack of evidence that can be generalizable as a whole to the country regarding the uptake of cervical cancer screening.

Objective: The aim of this review was to assess the pooled estimated uptake of CCa and to identify the major barriers to cervical cancer screening (CCS) uptake among adult women in Ethiopia.

Impact of nighttime human behavior on exposure to malaria vectors and effectiveness of using long-lasting insecticidal nets in the Ethiopian lowlands and highlands.

Background: Ethiopia continues to grapple with a persistent malaria burden, characterized by ongoing transmission and recurrent outbreaks. Human behavior influences both malaria exposure and the effectiveness of vector interventions, complicating malaria control efforts. Implementing tailored strategies that account for the complex interplay between human activities and vector behavior remains a challenge in both high- and low-transmission areas in Ethiopia, particularly for vulnerable highland populations and temporary labor migrants, due to lack of data.

Effective coverage of maternal and neonatal healthcare services in low-and middle-income countries: a scoping review.

Background: There is no consistent operationalization of effective coverage (EC) across studies. Therefore, this scoping review synthesized evidence on the definitions and measurement approaches, outcomes reported, and the factors that are associated with variations in quality-adjusted EC estimates of maternal and neonatal healthcare services in low- and middle-income countries.

Methods: Article search was conducted using PubMed, Embase, Google Scholar, and other databases.

Plasmodium falciparum and Schistosoma mansoni coinfections among the general population in Ethiopia: a systematic review and meta-analysis.

Background: Due to the overlapping endemic regions and the high burden of both infections, coinfection with Plasmodium falciparum and Schistosoma mansoni poses distinct public health concerns that require coordinated, multifaceted interventions. There are epidemiological studies on the coinfection of these two parasites in Ethiopia, and the results differ and are inconsistent from one region to another. Thus, the goal of this systematic review and meta-analysis was to ascertain Ethiopia's pooled prevalence of P.

Chromosome-scale assembly of the African yam bean genome.

Genomics-informed breeding of locally adapted, nutritious, albeit underutilised African crops can help mitigate food and nutrition insecurity challenges in Africa, particularly against the backdrop of climate change. However, utilisation of modern genome-assisted crop improvement tools including genomic selection and genome editing for many African indigenous crops is hampered by the scarcity of genomic resources. Here we report on the assembly of the genome of African yam bean (Sphenostylis stenocarpa), a tuberous legume crop that is indigenous to Africa.

A systematic review and individual bacterial species level meta-analysis of in vitro studies on the efficacy of ceftazidime/avibactam combined with other antimicrobials against carbapenem-resistant Gram-negative bacteria.

Background: Carbapenem-resistant Gram-negative bacteria (CR-GNB) develop resistance to many antimicrobials. To effectively manage infections caused by these organisms, novel agents and/or combinations of antimicrobials are required.

Objectives: Evaluated the in vitro efficacy of ceftazidime/avibactam in combination with other antimicrobials against CR-GNB.

Waning success: a 2013-2022 spatial and temporal trend analysis of malaria in Ethiopia.

Background: Despite consecutive decades of success in reducing malaria transmission, Ethiopia went off track towards its goal of malaria elimination by 2030, as outlined in the NMCP malaria strategy. Recent malaria outbreaks in Ethiopia are attributed to the emergence and spread of diagnostic and drug-resistant Plasmodium falciparum, increased insecticide resistance in major vectors and the spread of invasive Anopheles stephensi. The effects of the COVID-19 pandemic, environmental anomalies and internal conflicts have also potentially played a role in increasing malaria transmission.

Endemic Dietary Herb Extracts Reduce Acrylamide and Enhance Sensory Characteristics of Potato Chips.

This study evaluated the impact of soaking potato slices in water containing extracts from three endemic herbs, Lippia adoensis var. adoensis (kesse), Lippia adoensis var. koseret (koseret), and Thymus schimperi Ronninger (tosign), on acrylamide content and sensory attributes of fried potato chips.

Prevalence of cataract and its associated factors among adults aged 40 years and above living in Durame town, Southern Ethiopia, 2023: a community-based cross-sectional study.

Objective: This study aimed to assess the prevalence of cataract and associated factors among adults aged 40 years and above in Durame town, Southern Ethiopia.

Design: A community-based cross-sectional study was conducted using a systematic random sampling method.

Setting: The study was conducted in Durame town, Southern Ethiopia.

Correction: Skilled birth care uptake among women from socially disadvantaged minorities in the Kambata-Tambaro Zone, Southern Ethiopia.

[This corrects the article DOI: 10.1371/journal.pgph.

Correction: Home-based therapy and its determinants for children with cerebral palsy, exploration of parents' and physiotherapists' perspective, a qualitative study, Ethiopia.

[This corrects the article DOI: 10.1371/journal.pone.

Blood immune profiling of Ethiopian patients with breast cancer highlights different forms of immune escape.

Breast cancer (BC) is a leading cause of death worldwide, particularly also among African woman. In order to better stratify patients for the most effective (immuno-) therapy, an in depth characterization of the immune status of BC patients is required. In this study, a cohort of 65 Ethiopian patients with primary BC underwent immune profiling by multicolor flow cytometry on peripheral blood samples collected prior to surgery and to any other therapy.

Arbuscular mycorrhizal fungi improve morphological and yield performance of Eragrostis tef genotypes in Tigray, Ethiopia.

Arbuscular mycorrhizal fungi (AMF) form beneficial partnerships with most plant species, helping to improve crop resilience in tough environmental conditions. This paper analyzed how different genotypes responded to AMF inoculation, focusing on root colonization percentage (RCP) and the impact of AMF on above-ground agronomic traits. However, RCP alone may not fully explain genotype variation, and AMF effects cannot be judged solely on above-ground traits.

Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability.

The health, economic, and social burden of neglected tropical diseases (NTDs) in Africa remains substantial, with elimination efforts hindered by persistent sociopolitical instability, including ongoing conflicts among political and ethnic groups that lead to internal displacement and migration. Here, we explore how innovative technologies can support Africa in addressing NTDs amidst such instability, through analysis of WHO and UNHCR data and a systematic literature review. Countries in Africa facing sociopolitical instability also bear a high burden of NTDs, with the continent ranking second globally in NTD burden (33%, 578 million people) and first in internal displacement (50%, 31.

Immune landscape of the tumour microenvironment in Ethiopian breast cancer patients.

Background: The clinical management of breast cancer (BC) is mainly based on the assessment of receptor expression by tumour cells. However, there is still an unmet need for novel biomarkers important for prognosis and therapy. The tumour immune microenvironment (TIME) is thought to play a key role in prognosis and therapy selection, therefore this study aimed to describe the TIME in Ethiopian BC patients.

Horseshoe kidney with a retrocaval ureter: A case report from teaching hospital in Ethiopia.

Introduction: The combination of a horseshoe kidney with a retrocaval ureter in one patient is extremely rare.

Presentation Of Case: A 12-year-old adolescent presented with the compliant of absent testis in the right scrotum since birth with incidental radiologic finding of horseshoe kidney with retrocaval ureter.

Clinical Findings And Investigations: Physical examination was unremarkable except for a left non-palpable testis.

Co-infection of and soil-transmitted helminth among pregnant women in Abaya district, South Ethiopia: A community-based study.

Objectives: Co-infection of malaria with helminths poses significant risks, including fetomaternal hemorrhage, fetal growth retardation, spontaneous abortion, and preterm delivery. However, there is a lack of community studies to demonstrate the prevalence of co-infection of helminths with and soil-transmitted helminths (STH) and associated factors among pregnant women in Ethiopia.

Methods: A community-based cross-sectional study was conducted among 287 randomly selected pregnant women in the Abaya district from September to December 2022.

Additive effect of high transportation noise exposure and socioeconomic deprivation on stress-associated neural activity, atherosclerotic inflammation, and cardiovascular disease events.

Background: Noise exposure and lower socioeconomic status (SES) are both independently linked to increased cardiovascular disease (CVD) risk. Although these factors frequently coexist, their combined impact and the underlying pathophysiological mechanisms remain poorly understood.

Objectives: This study aimed to evaluate the joint effects of high transportation noise exposure and lower SES on major adverse cardiovascular events (MACE) and the role of the neural-arterial axis in mediating this relationship.

The impact of patients' preference for pharmaceutical dosage forms on medication discontinuation among patients attending Red Cross pharmacies in Northwest Ethiopia.

Medication discontinuation poses a significant challenge to the effectiveness of therapeutic interventions and overall patient treatment outcomes. Improving the pharmaceutical dosage forms' acceptability for patients, knowledge of proper ways for medication usage, and proper storage of medications play an indispensable role in enhancing patient safety. Thus the present study aimed to assess patients' preferences for pharmaceutical dosage forms, their knowledge of storage of medications, and factors associated with medication discontinuation among patients attending Red Cross pharmacies in Northwest Ethiopia.

Availability, price, and affordability of diabetes mellitus and thyroid dysfunction medicines in South Wollo zone, Northeast Ethiopia.

Background: Diabetes mellitus and thyroid dysfunction are prevalent endocrine disorders that impose enormous burdens on patients and countries. However, access to essential medicines remains inadequate in many low-income countries. This study evaluated medications' availability, price, and affordability for these conditions.