Shape Matters: Highly Selective Antimicrobial Bottle Brush Copolymers via a One-Pot RAFT Polymerization Approach.

The one-pot synthesis of antimicrobial bottle brush copolymers is presented. Reversible addition-fragmentation chain-transfer (RAFT) polymerization is used for the production of the polymeric backbone, as well as for the grafts, which were installed using a grafting-from approach. A combination of -isopropyl acrylamide and a Boc-protected primary amine-containing acrylamide was used in different compositions.