Publications by authors named "Melanie J Boileau"

Background: Pregnancy toxemia is a common metabolic disease of periparturient small ruminants. Information on its effects on metabolism and perinatal adaptation of newborn lambs and kids is lacking.

Objectives: Evaluate differences in morbidity, mortality, and common biochemical and hematologic variables between pregnancy toxemia kids (PT) and control kids (CON).

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Background: There are no commercially available handheld blood creatinine analyzers validated in goats.

Objectives: The objective of the study was to validate the accuracy of a handheld point-of-care (POC) analyzer (Nova StatSensor) for quantifying blood creatinine concentration in goats. A secondary objective was to compare this POC against a chemistry analyzer to classify goats as normal or having mild or moderate azotemia.

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Objective: To characterize frontal sinusitis unrelated to standard dehorning procedures in adult beef bulls.

Animals: 18 beef bulls > 2 years of age treated for frontal sinusitis at a veterinary medical teaching hospital between May 1999 and May 2014.

Procedures: Medical records were reviewed.

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Bdellovibrio bacteriovorus 109J is a Gram-negative predatory bacterium with obligate host dependency on other Gram-negative bacteria. This bacteriolytic predator collides with, enters, and establishes growth within the prey (host) periplasm, eventually lysing the prey cell wall to release fresh, motile B. bacteriovorus progeny.

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Asymmetrical signs of brainstem disease occur relatively infrequently in ruminants. The most common differential diagnoses include listeriosis, otitis media/interna, and pituitary abscess syndrome. Although these conditions produce signs of brainstem dysfunction, the diseases can usually be differentiated based on historical findings and subtle clinical differences.

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OBJECTIVE To determine the efficacy of Bdellovibrio bacteriovorus 109J for the treatment of calves with experimentally induced infectious bovine keratoconjunctivitis (IBK). ANIMALS 12 healthy dairy calves. PROCEDURES For each calf, a grid keratotomy was performed on both eyes immediately before inoculation with Moraxella bovis hemolytic strain Epp63-300 (n = 11 calves) or nonhemolytic strain 12040577 (1 calf).

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A 4-year-old female Suri alpaca was presented for evaluation of acute onset weakness, lethargy, and recent development of opacities in both eyes. On ophthalmic examination, bilaterally symmetrical corneal opacities were noted along the interpalpebral fissures with a few corneal blood vessels intermingled. A presumed diagnosis of calcific band keratopathy was made based on location and appearance.

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The broad spectrum of heat-related injury (HRI) and its associated lesions is well described in the human literature, with rare reports of similar findings in farm animals. In the current case series, lesions from 4 of 8 lambs that presented with clinical signs of heat stress are reported. Gross lesions at necropsy consisted of acute renal swelling and pallor in 2 of 4 lambs, muscle pallor in 2 of 4 lambs, and chronic bronchointerstitial pneumonia in each of the 4 lambs.

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The objective of this study was to determine the potential of Bdellovibrio bacteriovorus 109J as an alternative non-chemotherapeutic treatment of infectious bovine keratoconjunctivitis (IBK). To accomplish this, various parameters of B. bacteriovorus predation of Moraxella bovis were determined in vitro.

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Objective: To determine the pharmacokinetics after oral administration of a single dose of ponazuril to healthy llamas.

Animals: 6 healthy adult llamas.

Procedures: Ponazuril (20 mg/kg) was administered once orally to 6 llamas (day 0).

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Bovine coronavirus associated syndromes.

Vet Clin North Am Food Anim Pract

March 2010

Bovine coronaviruses, like other animal coronaviruses, have a predilection for intestinal and respiratory tracts. The viruses responsible for enteric and respiratory symptoms are closely related antigenically and genetically. Only 4 bovine coronavirus isolates have been completely sequenced and thus, the information about the genetics of the virus is still limited.

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Case Description: A 10-year-old Longhorn cow pregnant with a valuable fetus was evaluated because of progressive inspiratory dyspnea of 6 weeks' duration.

Clinical Findings: Physical examination findings were consistent with upper respiratory tract obstruction. A large pedunculated soft tissue mass was evident in the mid-dorsal aspect of the pharynx during palpation and endoscopic examination.

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Necropsy of 4 neonatal calves with a peracute syndrome of abdominal distention, diarrhea, dehydration, shock, and death revealed abomasal tympany, marked edema, hemorrhage, and emphysema of ruminal and abomasal walls and histopathologic lesions characteristic of forestomach acidosis. The presence of acid damage and the production of substantial quantities of gas strongly suggested that the pathogenesis of the syndrome involved exuberant fermentation of intragastric substrate. This supposition led to attempts to experimentally induce the syndrome by dosing neonatal calves with an alimentary tract flora, followed by milk replacer supplemented with excessive fermentable carbohydrate (D-glucose and cornstarch).

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Objective: To determine whether antemortem core needle biopsy and fine-needle aspiration of enlarged peripheral lymph nodes could be used to distinguish between inflammation and lymphosarcoma in cattle.

Design: Prospective study.

Animals: 25 cattle with enlarged peripheral lymph nodes.

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The objective of this study was to determine the serum pharmacokinetics of terbutaline in healthy cows. In the initial experiment, terbutaline was administered once as an intravenous (i.v.

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