Publications by authors named "Melania Martinez-Morillo"

Background: Seronegative elderly-onset rheumatoid arthritis (EORA) and polymyalgia rheumatica (PMR) have similar clinical characteristics making them difficult to distinguish based on clinical features. We hypothesized that the study of serum metabolome could identify potential biomarkers of PMR vs. EORA.

View Article and Find Full Text PDF

Objective: To determine the current state of Rheumatology in Catalonia and to update the information regarding previous studies.

Material And Methods Design: Observational, descriptive and cross-sectional study. Data collection from January to June 2017.

View Article and Find Full Text PDF
Article Synopsis
  • Some adult patients with autoimmune rheumatic diseases, particularly systemic lupus erythematosus (SLE) with anti-Ro/SSA antibodies, may have cardiac issues, prompting this study to explore cardiac screening utility.
  • The study involved 145 SLE patients who were tested for anti-Ro/SSA antibodies and underwent comprehensive cardiovascular assessments, including ECG and echocardiography.
  • Results showed no significant heart conditions or abnormalities in both anti-Ro/SSA-positive and negative patients, suggesting that routine cardiac evaluations may not be necessary for these patients.
View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed the retention rates and predictors of response to biologic disease-modifying anti-rheumatic drugs (bDMARDs) and apremilast in patients with psoriatic arthritis (PsA) over an 18-year period.
  • A total of 159 patients received various treatments, with a high discontinuation rate of 60%, primarily due to secondary failure (37%).
  • Key predictors for lack of response included male sex, number of swollen joints, and depression, with the best retention observed for anti-TNF agents like infliximab and etanercept.
View Article and Find Full Text PDF

MASEI is the main validated ultrasound score for the evaluation of enthesis. The lack of studies facing the agreement to achieve for the interpretation of the MAdrid Sonographic Enthesis Index (MASEI) among researchers from different centers in multicenter studies is of concern. The aim of this multicenter was to evaluate the interobserver reliability of MASEI.

View Article and Find Full Text PDF

Background And Objectives: Cutaneous polyarteritis nodosa (CPAN) is a comparatively rare form of vasculitis that affects small arteries and arterioles in the panniculus and dermo-subcutaneous junction. Limited information is available regarding its course in the European population. The aim of this study is to characterize the manifestations and prognostic markers of recurrence in CPAN.

View Article and Find Full Text PDF

Objective: To determine the current state of Rheumatology in Catalonia and to update the information regarding previous studies.

Material And Methods Design: Observational, descriptive and cross-sectional study. Data collection from January to June 2017.

View Article and Find Full Text PDF

Elderly-onset rheumatoid arthritis (EORA) and polymyalgia rheumatica (PMR) are common rheumatic diseases in older adults. Oxylipins are bioactive lipids derived from omega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids (PUFAs) that serve as activators or suppressors of systemic inflammation. We hypothesized that arthritis symptoms in older adults were related to oxylipin-related perturbations.

View Article and Find Full Text PDF

Objective: Septic arthritis is a medical emergency and crystal-induced arthritis is a risk factor for its development. If both occur simultaneously, crystal-induced arthritis may mask the diagnosis of infection and delay antibiotic therapy.

Method: Retrospective analysis of patients with coexistence of septic and crystal-induced arthritis.

View Article and Find Full Text PDF

We report a case of acute-onset multifocal vertebral osteitis with a marked impact on the patient's general health. The radiological, scintigraphic and magnetic resonance findings made it necessary to carry out a differential diagnosis to distinguish it from an infiltrative neoplastic process and determine whether it had an infectious or an inflammatory etiology. The presence of noninfectious multifocal osteitis and sternoclavicular arthritis and the subsequent development of plantar pustulosis pointed to SAPHO syndrome.

View Article and Find Full Text PDF

Behçet's disease is a systemic vasculitis characterized by the presence of oral and genital ulcers. Neurological involvement or neuro-Behçet is an uncommon manifestation. It manifestation has predominance in the male gender appearing 2 to 4 years after the first clinical manifestation.

View Article and Find Full Text PDF

Several case reports, small case series, and original research papers have recently suggested that the action of certain auto-antibodies related to connective tissue diseases may be responsible for significant cardiac rhythm disturbances in adults. The relationship between anti-Ro/SSA antibodies and congenital complete atrioventricular block is well recognized in the fetal heart. Herein we review the emerging evidences of the link to increased levels of anti-Ro/SSA antibodies with rhythm disorders of unknown origin in the adult.

View Article and Find Full Text PDF

Background And Objective: Secondary amyloidosis (AA) is a rare complication of rheumatic diseases.

Objective: The aim of this study was to determine the frequency of symptomatic amyloidosis AA in patients with spondyloarthropathy.

Patients And Method: Retrospective study (1984-2013).

View Article and Find Full Text PDF