Publications by authors named "Melani Marissa"

Hand eczema (HE) is a common condition seen in medical facilities, particularly during the COVID-19 pandemic. The effects of vitamin D on skin inflammation are diverse. The purpose of this study is to examine the relationship between vitamin D levels in healthcare workers as determined by serum 25(OH)D and the severity of HE.

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Macrophages respond against infection through interacting with vitamin D and vitamin D receptor (VDR). There has been no study analyzing the association between vitamin D and VDR with bacteriological index (BI) in leprosy patients in Indonesia. To analyze the serum level of 25- hydroxyvitamin D (25(OH)D) and plasma level of VDR as well as their association with BI in leprosy patients in Indonesia.

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Article Synopsis
  • The study investigates the effectiveness of the DPP® RDT test for diagnosing yaws in children aged 2-15 in Alor, Indonesia, highlighting a need for better diagnostic measures as recommended by the WHO.* -
  • A total of 197 children were examined, revealing that while 79.7% had yaws scars, only 3% tested positive for yaws using the DPP® RDT.* -
  • The findings show a low agreement (26.9%) between clinical features and RDT results, suggesting that clinical features alone should not be relied upon for diagnosing yaws in endemic regions.*
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Background: One of the indicators of achieved leprosy control is lower new cases of leprosy with grade 2 disability (G2D), while zero new pediatric case with G2D is one of the targets of The Global Leprosy Strategy. This study aimed to describe the characteristics of leprosy in children with G2D from seven provincial hospitals in Indonesia, spanning a period of five years.

Methods: This was a descriptive and retrospective study with cross-sectional design.

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Introduction: Melasma, and its variant chloasma, is an acquired and chronic disorder of hyperpigmentation, characterized by symmetrical hypermelanoses of the face. The exact pathogenesis of melasma remains unclear. Several hormones are thought to play a role, including thyroid hormones.

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Leg ulcers are a problem often found in the adult population, with a prevalence of 1 to 2% in the population. Vascular disease is the most common cause. Venous disorders that occur in the lower limbs are the main cause of lower leg ulcers compared to other vascular disorders.

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Onychomycosis contributes as many as half of all nail disorder cases. In 2017, the incidence of onychomycosis was 15% of all dermatomycosis cases at our hospital, a tertiary hospital in Indonesia, with only 25% of the patients achieving mycological cure. This study aims to identify the prognostic factors influencing the treatment outcome of onychomycosis Candida.

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