The validity and reliability of the CAMDEX-DS for assessing dementia in adults with Down syndrome in Brazil.

Objective: Alzheimer's disease occurs at a higher prevalence and an earlier age in individuals with Down syndrome (DS) than typically developing individuals. However, diagnosing dementia in individuals with intellectual disability remains a challenge due to pre-existing cognitive deficits. The aim of this study was to investigate the validity and reliability of the Brazilian version of the Cambridge Examination for Mental Disorders of Older People with Down's syndrome and Others with Intellectual Disabilities (CAMDEX-DS) for individuals with DS.

Child-focused treatment of pediatric OCD affects parental behavior and family environment.

This study aimed to investigate the impact of child-focused pediatric OCD treatment on parental anxiety, family accommodation and family environment. Forty-three parents (72.1% female, mean age±SD=43.

Bereavement and behavioral changes as risk factors for cognitive decline in adults with Down syndrome.

Background: Cognitive decline and Alzheimer's disease often affect older adults with Down syndrome (DS) much earlier than those in the general population. There is also growing evidence of the effects of negative life events on the mental health and behavior of individuals with intellectual disability. However, to our knowledge, this is the first study investigating objective cognitive decline following bereavement in aging individuals with DS.

Psychotic symptoms in older people without dementia from a Brazilian community-based sample.

Background: The international prevalence of psychotic symptoms in older subjects without dementia varies from 0.9% to 8.0%.