[Role of trehalose and glycogen in the survival of aging Saccharomyces cerevisiae cells].

The role of the storage carbohydrates trehalose and glycogen in the survival of aging Saccharomyces cerevisiae cells was studied. Culture aging for one week did not reduce cell viability. During this period, the cells accumulated the storage carbohydrates and raised the activity of the glycolytic enzymes hexokinase and phosphofructokinase.

[Effect of a low concentration of hydrogen peroxide on metabolism of blood cells].

Hydrogen peroxide is known to posses a wide range of physiological effects towards functional activity of cells. We have investigated the influence of H2O2 on the activity of glycolys in the native blood cells. Adding of hydrogen peroxide up to final concentration 50 microM led to decrease of activity some glycolytic enzymes.

[Arsenite-induced lipid peroxidation in Saccharomyces cerevisiae].

The ability of sodium arsenite at concentrations of 10(-2), 10(-4), and 10(-6) M to induce lipid peroxidation in Saccharomyces cerevisiae cells was studied. Arsenite at the concentrations 10(-2) and 10(-4) M enhanced lipid peroxidation and inhibited the growth of yeast cells. Enhanced lipid peroxidation likely induced oxidative damage to various cellular structures, which led to suppression of the metabolic activity of cells.

Pathomorphological peculiarities of microcirculatory bed in bronchial wall in workers employed in mining and chemical industry.

Morphological alterations of microvessels in bronchial mucosa and blood capillaries of alveolar septa during endobronchitis were examined in workers employed at a plutonium plant and not employed residents (Zheleznogorsk, Krasnoyarsk Region). Alterative, destructive, and dysadaptive changes in pulmonary vessels of workers were paralleled by developing reparative and adaptive processes in neighboring capillaries.

[The electrophysiological correlates of the individual-typological variants in stimulus assessment in 10- to 12-year-old children].

In children with various types of description of indefinite verbal and visual images stimuli the evoked potentials (EPs) were studied to these stimuli and control ones. Semantic reconstruction of indefinite stimuli is accompanied by an increase of activation level of late EPs components of the associative zones of the left hemisphere at perception of verbal stimuli and of the associative zones of the right hemisphere at perception of images. The subjects realizing semantic reconstruction of images produce EPs with predominance of activating influences by a number of EP parameters both at perception of indefinite images and of those definitely interpreted.

[Relation of visual evoked potentials to the integral characteristics of cognitive activity in 8- to 9-year-old children].

Amplitude and temporal parameters of evoked potentials (EPs) in response to a checkerboard pattern, picture of a house, the Russian word "dom", meaning house, combination of letters "DMO" and a number of other stimuli, correlated with indices of the verbal, nonverbal, and general intelligence as well as with those of the cognitive style "field dependence-independence". Maximum number of statistically significant correlations was found in the course of comparison of integrative cognitive characteristics and parameters of EPs to stimuli with increased semantic complexity. No interhemispheric differences were found in the character of interrelations between cognitive characteristics and parameters of EPs to verbal and spatially structured stimuli.

[Use of aliphatic amino acids by staphylococcus cells during pigment biosynthesis].

A study was made of a possibility of incorporation of labeled amino acids into the composition of carotinoid pigment of the Staph. aureus. The use in the biosynthesis of Staph.

[The influence of growth conditions on the composition of free amino acids in cells of staphylococcus and its pigmentless mutant].

The qualitative and quantitative composition of free amino acids was studied in the cells of Staphylococcus aureus, strain 209-P, and its pigmentless mutant B-6 grown in aerobic and anaerobic conditions. Aerobiosis stimulated accumulation of dicarboxylic and hydroxy amino acids, alanine and leucine, and pigment biosynthesis in the cells of Staphylococcus aureus. One amino acid has not been identified.