Electrophysiological studies of the interaction between ventricular myocardium and coronary artery in monkeys.

1. The electrical influence of the coronary arteries on ventricular muscle was investigated using strips of ventricle that included a section of coronary artery (cardiac preparation) and isolated coronary arteries dissected from the ventricle (arterial preparation). 2.

Endothelium-dependent contraction produced by acetylcholine and relaxation produced by histamine in monkey basilar arteries.

The present experiments were carried out to investigate the endothelium dependence of the responses to acetylcholine (ACh), arachidonic acid, and histamine in monkey basilar arteries. ACh and arachidonic acid caused endothelium-dependent contraction (EC) in both monkey and canine basilar arteries. The endothelium-derived contracting factor (EDCF) was probably thromboxane A2 (TxA2), as the EDC was attenuated by a cyclooxygenase inhibitor, TxA2 synthetase inhibitors, and TxA2 antagonists.

Electrical responses of coronary artery smooth muscle associated with the cardiac muscle action potential in the monkey.

1. In cardiac strips of the monkey ventricle which included a section of coronary artery (cardiac preparation), a depolarizing response, which appeared to be an excitatory junction potential (EJP), and a hyperpolarizing response were observed from the coronary artery smooth muscles when an action potential was generated in cardiac muscle by the application of electrical stimulation to the cardiac muscle alone. 2.

The role of hyperpolarization in the relaxation of smooth muscle of monkey coronary artery.

In monkey coronary arteries, outer and inner muscle had a similar resting potential (-39.5 and -40.0 mV).

Different electrical responses of outer and inner muscle of rabbit carotid artery to noradrenaline and nerves.

Electrical responses of outer and inner muscle of the rabbit carotid artery to electrical stimulation and noradrenaline were investigated. Mean values of the resting potential and space constant in the direction of the long axis of the cells were -47.3 mV and 1.

Electrophysiology and innervation of the smooth muscle of dog inferior vena cava.

1. Electrical properties of outer and inner muscles of three portions of dog inferior vena cava and their catecholaminergic innervation were investigated by microelectrode recording and an immunohistochemical technique. 2.

Electrical current-induced contraction in the smooth muscle of the rabbit aorta.

1. In the smooth muscle of rabbit aorta, the relationship between the change in membrane potential and the concentration evoked by current application was studied. 2.

Electrophysiological properties of the smooth muscle cell membrane of the dog coronary artery.

1. The electrical properties of dog coronary arterial smooth muscles were studied with the partitioned chamber method and Wheatstone Bridge method. Effects of intracellular and extracellular current and of field stimulation of nerve were examined.

Studies of the electrical excitability of aorta smooth muscle of rabbit.

1. Electrical records were made from the smooth muscle of rabbit aorta in normal solution and after excitation by noradrenaline, by the partitioned chamber method.2.

Rectification in the smooth muscle cell membrane of rabbit aorta.

1. The current-voltage relation of the smooth muscle cell membrane of rabbit aorta was determined by the partition method. 2.

Effect of clipping the coat of the Japanese macaque (Macaca fuscata) on the thermoregulatory responses.

Effect of clipping the coat of the Japanese macaque on thermoregulatory responses was studied. Heat production was significantly increased in clipped animals in comparison without clipped coats at ambient temperatures ranging from 5 to 25 degrees C. At ambient temperatures of 5, 15, and 25 degrees C tissue thermal conductance and cooling constant were significantly higher in clipped animals.

A comparison of thermoregulatory responses in the Japanese macaque (Macca fuscata) and the crab-eating macaque (Macaca irus) during cold exposure.

Thermoregulatory responses in four male adult Japanese macaques and four male adult crab-eating macaques, weighing 6-12 kg and 6.2-8 kg, respectively, were compared at ambient temperatures (Ta) ranging from 5 degrees C to 25 degrees C. The average values +/- S.

Current spread in the smooth muscle of the rabbit aorta.

1. The electrical responses of the smooth muscle cells of the rabbit aorta to both extracellular and intracellular stimulation were studied using the partitioned chamber and Wheatstone bridge method.2.

Biophysical effects of adrenaline on the smooth muscle of the rabbit common carotid artery.

Effects of adrenaline on the smooth muscle of the rabbit common carotid artery were studied by the partitional chamber method. The experiments on excitation-contraction coupling were carried out in isotonic Krebs solution; the other experiments were carried out in hypertonic Krebs solution. Adrenaline (10(-7) g/ml) caused rhythmical electrical and mechanical activity of arterial strips in isotonic Krebs solution.

Electrophysiological studies of the smooth muscle cell membrane of the rabbit common carotid artery.

The electrical responses of the smooth muscle cells of the rabbit common carotid artery to extracellular stimulation were studied in isotonic and hypertonic solution (1.7 times normal tonicity) with microelectrodes. No spontaneous electrical or mechanical activity was recorded when the tissue was in either isotonic or hypertonic solution.

Biophysical properties of the longitudinal smooth muscle of the guinea-pig rectum.

1. The membrane properties of the longitudinal muscle layer of the guinea-pig rectum were studied in hypertonic solution (twice the normal Krebs by addition of sucrose) by the micro-electrode technique. To produce the electrotonic potential and spike, stimulating partitions were used.