Publications by authors named "Mekala M Sujatha"
Aim: Role of mast cells in the development of oral lichen planus (OLP) and oral lichenoid reactions (OLR).
Material And Methods: The tissue slices used in this investigation were obtained from the archives of the Department of Oral Pathology and were formalin-fixed and embedded in paraffin. The sections were obtained from 40 cases of OLP that were identified by histological examination, as well as 40 cases of OLR.
Article Synopsis
- Oral submucous fibrosis (OSMF) is a chronic condition often caused by areca nut chewing, and this study focuses on how serum trace elements (copper, iron, zinc, selenium) affect its progression and potential for cancer.
- The research involved 80 participants categorized into four groups based on their areca nut usage and OSMF status, with blood samples taken to analyze trace element levels.
- Results showed significant increases in serum copper and zinc in individuals with malignant-transformed OSMF compared to healthy controls, suggesting elevated copper may be a key marker for diagnosing OSMF's malignant transformation, warranting further investigation into copper chelation as a treatment option.
Background Orofacial discomfort refers to various disorders that affect the mouth, jaws, and face. These conditions may substantially influence a person's quality of life (QoL). This kind of pain may be categorised into two primary classifications: acute and chronic.
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