Relationship of peak capillary blood lactate accumulation and body composition in determining the mechanical energy equivalent of lactate during sprint cycling.

Aim: A 15-s all-out sprint cycle test (i.e., νLa-test) and the post-exercise change in capillary blood lactate concentration is an emerging diagnostic tool that is used to quantify the maximal glycolytic rate.

Reliability of power output, maximal rate of capillary blood lactate accumulation, and phosphagen contribution time following 15-s sprint cycling in amateur cyclists.

Based on Mader's mathematical model, the rate of capillary blood lactate concentration (νLa) following intense exercise is thought to reflect the maximal glycolytic rate. We aimed to investigate the reliability of important variables of Mader's model (i.e.

Profiling microRNA expression during senescence and aging: mining for a diagnostic tool of senescent-cell burden.

In the last decade cellular senescence, a hallmark of aging, has come into focus for pharmacologically targeting aging processes. Senolytics are one of these interventive strategies that have advanced into clinical trials, creating an unmet need for minimally invasive biomarkers of senescent cell load to identify patients at need for senotherapy. We created a landscape of miRNA and mRNA expression in five human cell types induced to senescence and provide proof-of-principle evidence that miRNA expression can track senescence burden dynamically using transgenic p21 senescent cell clearance in HFD fed mice.

Wavelength-Dependent Effects of Photobiomodulation for Wound Care in Diabetic Wounds.

Photobiomodulation, showing positive effects on wound healing processes, has been performed mainly with lasers in the red/infrared spectrum. Light of shorter wavelengths can significantly influence biological systems. This study aimed to evaluate and compare the therapeutic effects of pulsed LED light of different wavelengths on wound healing in a diabetic (db/db) mouse excision wound model.

In vitro effects of 635 nm photobiomodulation under hypoxia/reoxygenation culture conditions.

Photobiomodulation (PBM), especially in the red wavelength range, has been demonstrated to be an effective treatment option for superficial and chronic wounds. However, ischemia and subsequent reperfusion can further challenge wound healing. Therefore, we investigated the effect of pulsed red LED light at 635 nm on cellular function in an in-vitro model of hypoxia/reoxygenation (H/R) challenge.

Human Placenta Laminin-111 as a Multifunctional Protein for Tissue Engineering and Regenerative Medicine.

Laminins are major components of all basement membranes surrounding nerve or vascular tissues. In particular laminin-111, the prototype of the family, facilitates a large spectrum of fundamental cellular responses in all eukaryotic cells. Laminin-111 is a biomaterial frequently used in research, however it is primarily isolated from non-human origin or produced with time-intensive recombinant techniques at low yield.

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Since 2003 bread and fine bakery products must not contain more than 350 μg Deoxynivalenol (DON). As a prerequisite for the label "Geprüfte Qualität"-Thüringen [proved quality Thuringia] and since coming into force of the respective evaluation prescription a total of 25 breads and 41 fine bakery products was investigated by ELISA with regard of this compound. In the 66 samples of the year 2003 no DON concentrations above the limit were detected and in the preparation period 2001/2002 only one sample exceeded the maximum.

Monitoring of fusarium toxins in cereals and feed-stuffs from thuringia (1998 - 2001).

From 1998 to 2001 a total of about 1172 conventionally and organically produced samples of wheat, rye, barley and triticale were examined for the presence of deoxynivalenol (DON) and zearalenone (ZON). Furthermore, feedstuffs for pigs were included in the monitoring of Fusarium toxins. DON and ZON analyses were performed using ELISA or HPLC.

[Importance of stable gastrointestinal microflora in growing animals].

A zysbiosis can be caused by food constituents. Food portions with 40% rye for chickens release a destabilisation of the gut flora. This can be prevented by effective stabilizers.

[Ergotropic efficacy of 2,3-dimethylquinoxaline-1,4-dioxide and 2-methylquinoxaline-1,4-dioxide in growing broilers using hydrocolloid-rich rations as well as broiler fattening feed].

2,3-dimethyl-quinoxaline-1,4-dioxide and 2-methyl-quinoxaline-1,4-dioxide proved to be ergotropic in the feeding of a hydrocolloid ration as well as of a broiler fattening feed. They are at least equal to Nitrovin. The ergotropic effect of the hydrocolloid ration was higher than that of the conventional ration.

[Effect of the addition of antibiotics on the fattening capacity of broilers fed optimum rations. 4. Lambdamycin].

A total of 3426 broilers were used in 3 fattening trials. The birds received supplements of the antibiotic lamdbamycine in amounts of 30 or 40 mg per kg of feed added to adequately balanced fattening rations. OTC supplements (40 mg per kg) which were an obligatory food component at the time of the trial were used as controls.