Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the flow cytometric assay data shown for the cell invasion assays in Figs. 2C, 4C and 5D, and the tumour images shown in Fig. 6A, were strikingly similar to data appearing in different form in other articles by different authors.
View Article and Find Full Text PDFLour. (MDL) is component used in traditional Chinese medicine that is widely distributed throughout southern China. MDL has been long utilized in clinical treatment for various conditions, such as inflammation.
View Article and Find Full Text PDFMicroRNA‑432 (miR‑432) has been studied in multiple tumors, but the expression status, biological functions and the mechanism of action of miR‑432 in glioblastoma multiforme (GBM) are yet to be elucidated. In the present study, miR‑432 expression in GBM was determined and its clinical significance was evaluated among patients with GBM. The effects on the malignancy of GBM in vitro and in vivo were examined in detail and the interactions between miR‑432 and insulin‑like growth factor 1 receptor (IGF‑1R) mRNA were then explored.
View Article and Find Full Text PDFBiomed Pharmacother
March 2018
Previous studies show that migration and invasion are the primary causes of death in patients with gastric carcinoma. Increasing evidences have been shown Interleukin-6 could stimulate cancer cells invasion and be associated with cancer development. However, its role in gastric cancer has never been investigated.
View Article and Find Full Text PDFClinical trials testing the effects of a single injection of adenovirus carrying the human hepatocyte growth factor gene (Ad-HGF) in patients with chronic ischemic heart failure failed to show consistent improvements in cardiac function. The aim of this study was to evaluate the efficacy of repeated injections of Ad-HGF in a rat model of postinfarct heart failure. Ad-HGF or Ad-green fluorescent protein (GFP) was administered to Sprague Dawley rat models of postinfarct heart failure via single or fractional repeated intrapericardial injection.
View Article and Find Full Text PDFResveratrol, for example widely present in the Chinese herbal medicine Polygonum cuspidatum, it is a natural phytoalexin, and has many biochemical activities, such as anti-tumor, anti-cardiovascular diseases, anti-bacterial, anti-inflammatory, anti-aging and other effects. This article will concentrate on the physical and chemical properties of resveratrol, the biological and pharmacological effects for its anticancer activities. An outlook is given to the development and application prospects in this drug.
View Article and Find Full Text PDFObjective: To investigate the resource of Tetrastigma hemsleyanum which was rare and endangered plant in She nationality in Zhejiang Province.
Methods: Using literature method, survey method, plots method and line method, the resource situation of artificial planting and wild resource in Zhejiang Province were investigated.
Results: It was a scarce and precious medicinal herb that wild resource was rare and endangered.