Primary central carcinoma ex pleomorphic adenoma of the mandible: report of a rare case and literature review.

We report a rare case of primary carcinoma ex pleomorphic adenoma (CXPA) of the mandible. A 13-year-old girl presented with a large mass, measuring about 30 cm in its greatest dimension, involving the mandible. She was referred to our department for surgery, and her postoperative course was uneventful; she is currently free from the disease 48 months after surgery.

Effects of cigarette smoke condensate and nicotine on human gingival fibroblast-mediated collagen degradation.

Background: Members of the matrix metalloproteinase (MMP) family have been shown to be involved in periodontal disease. Risk factors for periodontal disease include tobacco smoking. Cigarette smoke condensate (CSC) is comprised of thousands of chemicals.

Malignant transformation of oral lichen planus: a retrospective study of 23 cases.

Objective: Oral lichen planus (OLP) is a common mucocutaneous disease with malignant transformation potential. The aim of this retrospective study was to investigate the characteristics of patients with OLP who developed oral squamous cell carcinoma (OSCC).

Method And Materials: The medical records of 2,119 patients with OLP at West China College of Stomatology, China, from 1951 to 2006, were reviewed.

[Clinical evaluation of composite inlays in defective molars].

Objective: To evaluate clinical effect of composite inlays in the defective molars.

Methods: A total of 200 defective molars from 163 patients were divided into two groups, including 100 molars of each. One group was restored with the direct composite inlays and another group with the traditional composite fillings.

[Effect of focal adhesion kinase on biological characteristics of Tca8113 tongue squamous cell carcinoma].

Objective: To investigate the effect of FAK on biological characteristics of tongue squamous cell carcinoma cell Tca8113.

Methods: Lipofect was used to transfect FAK into Tca8113 cell lines. The difference in expression of FAK between the transfected and non-transfected cell lines was detected by immunofluorescence assay.

[Expression and clinical significance of focal adhesion kinase in oral squamous cell carcinoma].

Objective: To study the correlation between expression levels of focal adhesion kinase (FAK) in oral squamous cell carcinoma (OSCC) and clinical prognosis with pathologic parameters.

Methods: Eighty paraffin embedded tissue specimens of OSCC were studied by immunohistochemistry. The data was analyzed by SPSS statistical software.