Publications by authors named "Meixia Ke"
Article Synopsis
- Long non-coding RNA SNHG18 is found to be downregulated in bladder cancer (BC) tissues and is linked to patient survival rates.
- Overexpression of SNHG18 was shown to inhibit BC cell proliferation both in lab tests and animal models, indicating its potential as a therapeutic target.
- The study revealed that SNHG18 works by suppressing c-Myc expression, which in turn promotes the transcription of p21, leading to cell cycle arrest and reduced cancer cell growth.
Due to the lack of effective early diagnostic measures and treatment methods, bladder cancer has become a malignant tumor that seriously threatens people's lives and health. Here, we reported that LINC00162, a super-enhancer long noncoding RNA, was highly expressed in bladder cancer cells and tissues. And LINC00162 was negatively correlated with neighboring PTTG1IP expression.
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