Flexible wafer-scale bifunctional metasurface based on nanoimprinting.

Metasurfaces have demonstrated remarkable capabilities in manipulating light fields across diverse applications. However, current research tends to examine these functionalities in isolation, prompting a growing interest in integrating different functionalities within a singular metasurface device. In this paper, we propose and experimentally demonstrate a bifunctional metasurface capable of providing concealment and sensing functions simultaneously.

Salvage Perioperative Interstitial High-Dose-Rate Interventional Radiotherapy (Brachytherapy) for Local Recurrences of the Chest Wall Following Mastectomy and Previous External Irradiation.

(1) Background: To investigate the technical feasibility, safety, and efficacy of interstitial perioperative high-dose-rate interventional radiotherapy (HDR-IRT, brachytherapy) as a local salvage treatment combined with surgery for local chest wall recurrences following mastectomy and subsequent external beam radiation treatment (EBRT). (2) Methods: A retrospective analysis of 56 patients treated with interstitial HDR-IRT in combination with local surgery of a chest wall recurrence of breast cancer after previous treatment with mastectomy and EBRT from 2008 to 2020. (3) Results: Local recurrence following HDR-IRT was encountered in seven (12.

Charge Neutralization Strategy to Construct Salt-Tolerant and Cell-Permeable Nanoprobes: Application in Ratiometric Sensing and Imaging of Intracellular pH.

Intracellular pH homeostasis is essential for the survival and function of biological cells. Negatively charged molecular probes, such as pyranine (HPTS), tend to exhibit poor salt tolerance and unsatisfactory cell permeability, limiting their widespread use in intracellular assays. Herein, we explored a charge neutralization strategy using multicharged cationic nanocarriers for an efficient and stable assembly with the pH-sensitive HPTS.

Circ_0007331 knock-down suppresses the progression of endometriosis via miR-200c-3p/HiF-1α axis.

Endometriosis is considered a benign gynaecological disease with cancer-like characterizations, which has a high incidence among women of reproductive age. However, this disease has so far lacked timely diagnosis and effective treatment owing to its unclear aetiology. In this study, we identified aberrant high expression of circ_0007331 in ectopic endometrial cells by comparing the endometrial samples from patients with and without endometriosis.

mInscuteable regulates meiotic spindle organization during mouse oocyte meiotic maturation.

Establishment of cellular polarity is one of the key events during oocyte maturation. Inscuteable (Insc) has been identified as a key regulator of cell polarity during asymmetric division in Drosophila. However, the function of its evolutionarily conserved mammalian homologue, mInscuteable (mInsc), in mouse meiotic maturation is not clear.

Micelle-Mediated Chemiluminescence as an Indicator for Micellar Transitions.

The structural phase of micelles plays an important role in controlling the micellar performance. Despite the great developments of some advanced characterization techniques, it remains challenging to achieve fast and sensitive determination of micellar transitions in solution. Herein, a novel indicator system for micellar transitions was developed based on the micelle-mediated peroxyoxalate chemiluminescence that showed a sensitive response toward the changes of micellar morphologies.

Reconstructive laparoscopic prolapse surgery to avoid mesh erosions.

Introduction: The objective of the study is to examine the efficacy of the purely laparoscopic reconstructive management of cystocele and rectocele with mesh, to avoid the risk of erosion by the graft material, a well known complication in vaginal mesh surgery.

Material And Methods: We performed a prospective, single-case, non-randomized study in 325 patients who received laparoscopic reconstructive management of pelvic organe prolaps with mesh. The study was conducted between January 2004 and December 2012 in a private clinic in India.