Publications by authors named "Meiting Ban"
Background: Cumulative evidence has consistently shown that white matter (WM) disruption is associated with cognitive decline in geriatric depression. However, limited research has been conducted on the correlation between these lesions and cognitive performance in untreated young adults with major depressive disorder (MDD), particularly with the specific segmental alterations of the fibers.
Method: Diffusion tensor images were performed on 60 first-episode, treatment-naïve young adult patients with MDD and 54 matched healthy controls (HCs).
Article Synopsis
- Betel quid (BQ) is a widely used psychoactive agent with around 600 million users, and those with dependence disorder display deficits in executive function.
- The study employed resting-state functional MRI to compare 55 BQ-dependent individuals with 54 healthy controls, revealing significant differences in the connectivity and functionality of the executive control network (ECN).
- Findings indicated impaired executive function and weaker functional connectivity in BQD patients, suggesting potential targets for future intervention strategies.
Background: Betel quid (BQ) is the fourth most popular psychoactive agent worldwide. Neuroimaging studies have showed that substance-addicted individuals including alcohol, heroin, nicotine and other addictive substance exhibit altered activity patterns of the salience network (SN). However, no study has yet investigated the neural correlates of the resting-state SN and BQ dependence (BQD)-related physiopathological characteristics.
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- A study investigated the differences in neuro-metabolite concentrations in the anterior cingulate cortex (ACC) between young adults with major depressive disorder (MDD) and healthy controls, focusing on two subregions: the pregenual ACC (pACC) and anterior midcingulate cortex (aMCC).
- Results showed that MDD patients had higher levels of glutamate and glutamine in the pACC and higher myo-inositol in the aMCC compared to controls, indicating pronounced metabolic changes in the MDD group.
- The findings suggest that the pACC and aMCC may have different roles in MDD, highlighting the regional metabolic differences in the ACC and contributing to