Publications by authors named "Meita Ucche"

Background: Chemotherapy has a substantial role in decreasing the risk of recurrence and mortality in breast cancer (BC) in a dose-dependent manner where a low relative dose intensity (RDI) is associated with unfavorable outcomes. Several baseline clinicopathological factors, including pro-inflammatory biomarkers, were found to be significant determinants of low RDI. This study aimed to explore the occurrence of low RDI and its influencing factors in women with BC.

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Article Synopsis
  • Chemotherapy-induced peripheral neuropathy (CIPN) negatively impacts the quality of life for breast cancer patients, leading to a study that aimed to develop a prediction model using the classification and regression tree (CART) algorithm.
  • The research involved 170 breast cancer patients and used a patient-reported assessment to identify CIPN occurrences, ultimately finding that high C-reactive protein (CRP) levels, BMI, and marital status are key predictors of CIPN.
  • The CART model achieved an accuracy of 65.9% and highlighted the importance of CRP levels and neutrophil-to-lymphocyte ratios in predicting CIPN, suggesting this model could be useful for developing individualized patient care strategies in the future.
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Background: Studies to confirm the efficacy and safety of convalescent plasma (CP) as an adjunctive treatment for COVID-19 are still required especially for the countries where standard treatments are unevenly distributed.

Methods: A non-randomized comparative study was done from June - September 2020 in Dr. Sardjito Hospital, Yogyakarta, Indonesia.

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Metastatic breast cancer may present as a pericardial effusion that can progress to a life-threatening cardiac tamponade. Pericardial window followed by initial chemotherapy needs to be immediately applied in order to achieve a favorable outcome.

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