Publications by authors named "Meirui Ma"
Extracellular vesicles (EVs), secreted by most cells, act as natural cell-derived carriers for delivering proteins, nucleic acids, and organelles between cells. Mitochondria are highly dynamic organelles responsible for energy production and cellular physiological processes. Recent evidence has highlighted the pivotal role of EVs in intercellular mitochondrial content transfer, including mitochondrial DNA (mtDNA), proteins, and intact mitochondria.
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- Autophagy helps cells in bones, like osteocytes, to stay healthy and survive, especially when they are under pressure from forces like compression.
- The researchers found that when osteocytes were squeezed, they showed increased signs of autophagy, which means they cleaned up and recycled their parts better.
- This process also helped other bone cells, promoting healthy bone growth and lowering the activity of cells that break down bone, which could be useful for treating bone diseases.
Neuropeptide Y (NPY) is a widespread hormone in the central and peripheral nervous systems that maintains body homeostasis. Central actions of hypothalamic NPY have been identified in bone metabolism. Osteocytes are the main source of NPY in bone tissue, indicating that osteocytic NPY could be a local alternative pathway for hypothalamic mediated regulation of bone and bone cells.
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