Publications by authors named "Meiqi Lai"

Introduction: Family caregivers play an indispensable role in the care of solid organ transplant patients, undertaking a wide range of tasks from basic daily care to complex medical management. However, these responsibilities come with substantial challenges, placing additional strain on caregivers who bear significant physical, emotional, financial and social burdens, along with numerous unmet support needs. Currently, the exploration of challenges and support needs among family caregivers in the caregiving process is limited to primary research, lacking a synthesised and comprehensive understanding of the issues.

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Article Synopsis
  • Recent advancements in nanomedicine have led to the creation of nanoparticles that can target tumors effectively due to the enhanced permeability and retention (EPR) effect, although high interstitial fluid pressure (IFP) in solid tumors poses a challenge for effective delivery.
  • This study explored the use of low-frequency non-focused ultrasound (LFNFU) combined with ultrasonic targeted microbubble destruction (UTMD) to reduce IFP and improve the accumulation of different sized Cy5.5-conjugated mesoporous silica nanoparticles (Cy5.5-MSNs) in tumors.
  • Results showed that UTMD significantly increased the delivery of Cy5.5-MSNs, achieving a sevenfold higher accumulation at an optimal acoustic pressure of
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Objective: To observe the impacts of acupuncture on depressive mood and sleep quality in patients with comorbid mild-to-moderate depressive disorder and insomnia, and explore its effect mechanism.

Methods: A total of 60 patients with comorbid mild-to-moderate depressive disorder and insomnia were randomly divided into an observation group (30 cases, 1 case dropped off) and a control group (30 cases, 2 cases dropped off). In the observation group, acupuncture and low frequency repeated transcranial magnetic stimulation (rTMS) were combined for the intervention.

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Objective: To observe the effect of electroacupuncture (EA) at back- points of five on fatigue status, quality of life and motor cortical excitability in patients with chronic fatigue syndrome (CFS), so as to explore the possible mechanism of EA for CFS.

Methods: A total of 72 patients with CFS were randomized into an EA group (36 cases, 4 cases dropped off) and a sham EA group (36 cases, 3 cases dropped off). In the EA group, EA at Ganshu (BL 18), Xinshu (BL 15), Pishu (BL 20), Feishu (BL 13) and Shenshu (BL 23) was adopted, with continuous wave, 2 Hz in frequency.

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Based on the thinking of integrative and holistic acupuncture and moxibustion, - proposes to treat depression complicated with obsessive-compulsive disorder from perspective of heart and gallbladder. In clinical practice, the treatment pattern of "acupuncture at the top priority, followed by moxibustion, and consolidation at the end" is applied, acupuncture, refined moxibustion, intradermal needle and other therapies are comprehensively adopted, acupoints on the heart meridian, pericardium meridian and gallbladder meridian are selected or back- points and front- points of the heart, gallbladder and pericardium are matched, and the acupoints on the conception vessel and governor vessel and with the functions of tonifying kidney and regulating are added to calm the heart and tranquilize the mind, so as the symptoms of depression and obsessive-compulsive can be effectively relieved.

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