A case report of phacolytic glaucoma in lens cortex behind posterior capsule: A CARE-compliant article.

Rationale: Phacolytic glaucoma (PLG), a secondary open-angle glaucoma caused by high molecular weight proteins leaking through the capsule of a hypermature cataract. Leakage of liquefied lens cortex behind the posterior capsule is rare. In this paper, we review a case of phacolytic glaucoma in the lens cortex behind posterior capsule.

Effectiveness of smartphone-assisted cardiac rehabilitation: a systematic review and meta-analysis.

Purpose: To explore the effectiveness of smartphone-assisted home cardiac rehabilitation and whether it can be used as a remote detection method to promote home cardiac rehabilitation.

Methods: Four databases were searched to collect randomized controlled trials (RCTs) about smartphone-assisted cardiac rehabilitation. The Cochrane risk-of-bias tool was used to assess the methodological quality of the included studies.

Functional abdominal pain disorders in children in southern Anhui Province, China are related to academic stress rather than academic performance.

Background: Functional abdominal pain disorders (FAPDs) are one of the most common gastrointestinal disorders in children. The aim of this study was to investigate the prevalence of FAPDs in children in southern Anhui Province, China and their association with academic stress.

Methods: In this cross-sectional survey, we randomly selected children aged 6-17 years from 11 public schools in southern Anhui Province.

Regio- and Stereoselective Organocatalyzed Relay Glycosylations To Synthesize 2-Amino-2-deoxy-1,3-dithioglycosides.

Herein, we describe a novel methodology for the regio- and stereoselective convergent synthesis of 2-amino-2-deoxy-dithioglycosides via one-pot relay glycosylation of 3--acetyl-2-nitroglucal donors. This unique organo-catalysis relay glycosylation features excellent site- and stereoselectivity, good to excellent yields, mild reaction conditions, and broad substrate scope. 2-Amino-2-deoxy-glucosides/mannosides bearing 1,3-dithio-linkages were efficiently obtained from 3--acetyl-2-nitroglucal donors in both stepwise and one-pot glycosylation protocols.

The role of long noncoding RNAs in therapeutic resistance in cervical cancer.

Cervical cancer is one of the common tumors and often causes cancer-related death in women. Chemotherapy is a common cancer therapy, which displays a pivotal clinical benefit for cancer patients. However, chemoresistance becomes a big obstacle for failure of treatment in cancer patients.

Pentagalloylglucose suppresses the growth and migration of human nasopharyngeal cancer cells via the GSK3β/β-catenin pathway in vitro and in vivo.

Background: Nasopharyngeal carcinoma (NPC) is a type of malignant squamous cell tumour originating from the nasopharynx epithelium. Pentagalloylglucose (PGG) is a natural polyphenolic compound that exerts anticancer effects in many types of tumours. However, the role and underlying mechanism of PGG in NPC cells have not been fully defined.

Light-driven selective aerobic oxidation of (iso)quinoliniums and related heterocycles.

Selective C1-H/C4-H carbonylation of -methylene iminium salts, catalyzed by visible-light photoredox and oxygen in the air, has been reported. A ruthenium complex acts as a chemical switch to conduct two different reaction pathways and to afford two different kinds of products. In the absence of the ruthenium complex, the Csp-H bonds adjacent to the nitrogen atoms are oxidized to α-lactams by the -methyleneiminium substrates themselves as photosensitizers.

Heavy metals in water and surface sediments of the Fenghe River Basin, China: assessment and source analysis.

This paper combines environmental science, inorganic chemistry, water quality monitoring and other disciplines to analyze and assess the heavy metals in the water bodies and sediments of the Fenghe River Basin (FRB) in Shaanxi Province, and reveal their sources. The Water Quality Index (WQI), Nemero Index (Pn), Geological Accumulation Index (I-geo) and Potential Ecological Risk Index (RI) are used to assess heavy metals in water and sediments. Pearson correlation analysis (CA), hierarchical cluster analysis (HCA), principal component analysis (PCA) and positive matrix factorization (PMF) models are used to study the relationship and source of heavy metals.

Exploring sustainable solutions for the water environment in Chinese and Southeast Asian cities.

Water is essential for human activities and economic development, and the water environment significantly influences ecological balance and global climate. China and Southeast Asia are the most populous areas in the world, and their water resources are deteriorating day by day. We focus on five representative cities such as, Beijing, Jakarta, Hanoi, Kathmandu and Manila to investigate water-environmental problems with the ultimate goal of providing recommendations for sustainable urban water management.

Control and remediation methods for eutrophic lakes in the past 30 years.

Accelerated eutrophication, which is harmful and difficult to repair, is one of the most obvious and pervasive water pollution problems in the world. In the past three decades, the management of eutrophication has undergone a transformation from simple directed algal killing, reducing endogenous nutrient concentration to multiple technologies for the restoration of lake ecosystems. This article describes the development and revolution of three remediation methods in application, namely physical, chemical, and biological methods, and it outlines their possible improvements and future directions.

Airborne phthalates in indoor environment: Partition state and influential built environmental conditions.

Exposure to phthalates has recently become a major public health concern. The information of indoor airborne phthalates and their air-particle partition in real indoor environmental condition is still limited. In this study, the gas- and PM-concentrations of 7 phthalates in 40 residences were concurrently measured in summer and winter.

Anti-inflammatory activity of isobutylamides from zanthoxylum nitidum var. tomentosum.

Inflammation is a very common and important basic pathological process. There is still a great need for the isolation of effective anti-inflammatory agents from plants. In this paper, five new isobutylamides, zanthoxylumamides E-I (1-5), and four known isobutylamides (6-9) were isolated from Zanthoxylum nitidum var.

Water quality trend assessment in Jakarta: A rapidly growing Asian megacity.

Megacities are facing serious water pollution problems due to urbanization, rapid population growth and economic development. Water is an essential resource for human activities and socio-economic development and water quality in urban settings has important implications for human and environmental health. Urbanization and lack of sewerage has left the water in Jakarta, Indonesia in a heavily polluted condition.

Synthesis and discovery of asiatic acid based 1,2,3-triazole derivatives as antitumor agents blocking NF-κB activation and cell migration.

A series of asiatic acid (AA) based 1,2,3-triazole derivatives were designed, synthesized and subjected to a cell-based NF-κB inhibition screening assay. Among the tested compounds, compound displayed impressive NF-κB inhibitory activity with an IC value in the low micromolar range. A molecular docking study was performed to reveal key interactions between and NF-κB in which the 1,2,3-triazole moiety and the hydroxyl groups of the AA skeleton were important for improving the inhibitory activity.

Efficiency of Neuromuscular Electrical Stimulation and Transcutaneous Nerve Stimulation on Hemiplegic Shoulder Pain: A Randomized Controlled Trial.

Objective: To compare the efficacy of neuromuscular electrical stimulation (NMES) and transcutaneous nerve stimulation (TENS) on hemiplegic shoulder pain (HSP).

Design: This is a prospective randomized controlled trial.

Setting: A rehabilitation hospital.

Impact of forest maintenance on water shortages: Hydrologic modeling and effects of climate change.

The importance of water quantity for domestic and industrial water supply, agriculture, and the economy more broadly has led to the development of many water quantity assessment methods. In this study, surface flow and soil water in the forested upper reaches of the Yoshino River are compared using a distributed hydrological model with Forest Maintenance Module under two scenarios; before and after forest maintenance. We also examine the impact of forest maintenance on these variables during extreme droughts.

Preparation of ureido-functionalized PVA/silica mesoporous fibre membranes via electrospinning for adsorption of Pb and Cu in wastewater.

Ureido-functionalized mesoporous polyvinyl alcohol/silica composite nanofibre membranes were prepared by electrospinning technology and their application for removal of Pb and Cu from wastewater was discussed. The characteristics of the membranes were investigated by scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and N adsorption-desorption analysis. Results show that the membranes have long fibrous shapes and worm-like mesoporous micromorphologies.

Poly (ionic liquid)-Based Breath Figure Films: A New Kind of Honeycomb Porous Films with Great Extendable Capability.

In this work, we reported a new method for the convenient fabrication of various functional porous films, which cannot be directly generated using breath figures (BFs). A series of polystyrene-b-poly (ionic liquid) (PS-b-PIL) block copolymers were employed for BFs process for the first time. It was found that PS-b-PIL could form well-defined BFs porous structure.

Discovery of dehydroabietic acid sulfonamide based derivatives as selective matrix metalloproteinases inactivators that inhibit cell migration and proliferation.

A series of dehydroabietic acid (DHAA) dipeptide derivatives containing the sulfonamide moiety were designed, synthesized and evaluated for inhibition of MMPs as well as the effects of in vitro cell migration. These compounds exhibited relatively good inhibition activity against MMPs with IC values in low micromolar range. A docking study of the most active compound 8k revealed key interactions between 8k and MMP-3 in which the sulfonamide moiety and the dipeptide group were important for improving activity.

Toxic effects of NH-N on embryonic development of Bufo gargarizans and Rana chensinensis.

Although nitrogen fertilizer is commonly used worldwide, little information is currently available about NH-N toxicity on amphibians. This study determined the acute and chronic toxic effects of NH-N on two native Chinese amphibian species (Bufo gargarizans and Rana chensinensis), and compared the negative sensitivity of different embryos to NH-N. Static renewal aqueous exposures were performed using B.

AIE-induced fluorescent vesicles containing amphiphilic binding pockets and the FRET triggered by host-guest chemistry.

A series of tetraphenylethylene (TPE)-bile acid conjugates was described. It was found that the synergetic combination of the distinct properties of TPE and bile acid units could directly afford uniform fluorescent vesicles with amphiphilic binding pockets in the membrane. This structural features of such vesicles provides a unique opportunity for facile construction of functional chemical systems through host-guest chemistry.

A polydopamine layer as the nucleation center of MOF deposition on "inert" polymer surfaces to fabricate hierarchically structured porous films.

Effective deposition of MOFs on "inert" solid surfaces is very challenging. In this work, we found that polydopamine, which can be facilely and tightly formed on any types as well as any forms of solid surfaces, could be used as an effective nucleation center for MOF deposition. Based on this finding, various MOFs were successfully deposited onto nanofibrous polymer membranes, especially the commercially available "inert" ones, affording hierarchically structured porous films.

Magnetic metal-organic frameworks: γ-Fe2O3@MOFs via confined in situ pyrolysis method for drug delivery.

A general one-step in situ pyrolysis route for the construction of metal-organic frameworks encapsulating superparamagnetic γ-Fe2O3NPs dispersed in the confined cavities of MOFs homogeneously is described. The integration of γ-Fe2O3 NPs or clusters into MOFs can endow these porous materials with superparamagnetic element. By the combination of the thermal stability of MOFs and pyrolysis of metal triacetylacetonate complex at matched conditions, the porous structure of MOFs are well maintained while the size-induced superparamagnetic property of nano γ-Fe2O3 is obtained.