Exercise for frailty research frontiers: a bibliometric analysis and systematic review.

Background: Exercise intervention is a method of improving and preventing frailty in old age through physical exercise and physical activity. It has a positive impact on many chronic diseases and health risk factors, in particular cardiovascular disease, metabolic disease, osteoporosis, mental health problems and cancer prevention, and exercise therapies can also fight inflammation, increase muscle strength and flexibility, improve immune function, and enhance overall health. This study was aimed to analyze research hotspots and frontiers in exercise therapies for frailty through bibliometric methods.

Epidemiology and grade 2 disability of leprosy among migrant and resident patients in Guangdong: an unignorable continued transmission of leprosy.

Introduction: Leprosy remains a major public health concern worldwide and one of the leading causes of disability. New cases of leprosy with grade 2 disability (G2D) often reflect delayed detection due to the limited capacity of the health system to recognize leprosy early. This study aimed to describe the epidemiology and G2D of leprosy among migrant and resident patients with leprosy in Guangdong province, China.

Serum brain-derived neurotrophic factor (BDNF) as predictors of childhood neuroblastoma relapse.

Background: Neuroblastoma (NB) is a childhood malignant tumor,50% of high-risk NB children still have recurrence, and the long-term survival rate is very low. NB tumors expressing high levels of BDNF/TrkB are associated with poor survival outcomes.In this study, we show that the trends of serum concentration of BDNF at different growth stages after birth, and explore the relationship with NB replase.

Machine Learning Predicts the Methane Clumped Isotopologue (CHD) Distributions Constrain Biogeochemical Processes and Estimates the Potential Budget.

Methane (CH) is a matter of environmental concern; however, global methane isotopologue data remain inadequate. This is due to the challenges posed by high-resolution testing technology and the need for larger sample volumes. Here, worldwide methane clumped isotope databases ( = 465) were compiled.

How does the integration of cultural and tourism industries impact the value added to tourism value chain: Evidences from Jiangsu Province of China.

China has been fully implementing the policy of the cultural and tourism industrial integration since 2018. However, the value-added benefits of this policy are not prominent, and the relationship between industrial integration and the value added to the tourism value chain was seldom addressed by researchers. In the context of China's high-quality development, it is necessary to conduct the impact of the integration of cultural and tourism industries on the value added to tourism value chain.

Chemical Constituents and Hypoglycemic Mechanisms of in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.

This study aimed to systematically explore the chemical constituents of and its hypoglycemic effect by UPLC-ESI-Q-Orbitrap, network pharmacology and in vivo experiment. The chemical constituents of were qualitatively analyzed, and the hypoglycemic compounds were quickly identified. Network pharmacological analysis and molecular docking technique were applied to assist in the elucidation of the hypoglycemic mechanisms of .