Publications by authors named "Meiling Kou"
Contagious Eczema (CE), caused by ORFV, impacts sheep and goats globally, with severe symptoms and economic losses. The ORFV situation in Yunnan, China, was unclear before 2021-2023 study. Eleven scab samples from goats on small farms in three Yunnan municipalities were collected.
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- Two virus strains, JC13C644 and JC13C673, were discovered in Yunnan Province, China, and were shown to cause disease in mammalian cells and suckling mice.
- Whole-genome sequencing revealed that these viruses are closely related to Eastern group EHDV, particularly EHDV-10 from Japan, indicating a significant genetic similarity.
- A survey found virus-neutralizing antibodies in cattle and goats, suggesting EHDV-10 circulates in local domestic animals, marking the first detection of the virus in China and highlighting the need for increased monitoring of EHDV infections.