Value-modulated attentional capture is augmented by win-related sensory cues.

Attentional prioritisation of stimuli in the environment plays an important role in overt choice. Previous research shows that prioritisation is influenced by the magnitude of paired rewards, in that stimuli signalling high-value rewards are more likely to capture attention than stimuli signalling low-value rewards; and this attentional bias has been proposed to play a role in addictive and compulsive behaviours. A separate line of research has shown that win-related sensory cues can bias overt choices.

Effect of combination therapy with neural stem cell transplantation and teramethylpyrazine in rats following acute spinal cord injury.

Objectives: This study was to explore the effects of teramethylpyrazine (TMP) administered in conjunction with neural stem cell transplantation on motor function, pathological lesions and the Janus kinase (JAK)2/signal transducer and activator of transcription 3 signal transduction pathway in rats following acute spinal cord injury (SCI).

Methods: Female Sprague-Dawley rats were randomly divided into sham, model, neural stem cells (NSCs) and NSCs+TMP groups. Motor function was evaluated using the Basso, Beattie, Bresnahan scale.

MicroRNA-211-5p attenuates spinal cord injury via targeting of activating transcription factor 6.

The recovery of spinal cord injury (SCI) involves multiple factors, of which miRNAs take an important part. In this study, we evaluated the function of microRNA-211-5p (miR-211-5p) on SCI in a rat model. SCI model was established using modified Allen's weight-drop method and Basso-Bcattie-Bresnahan score was applied to assess the locomotor function.

Investigation of key miRNAs and their target genes involved in cell apoptosis during intervertebral disc degeneration development using bioinformatics methods.

Background: The aim of this study was to identify important miRNAs and their target genes involved in cell apoptosis in intervertebral disc degeneration (IDD) patients.

Methods: The dataset, GSE63492, was obtained from the gene expression omnibus platform. After preprocessing, the differentially expressed miRNAs (DEMs) and their target genes were identified using the Limma package and miRWalk2.

Meta analysis of olfactory ensheathing cell transplantation promoting functional recovery of motor nerves in rats with complete spinal cord transection.

Objective: To evaluate the effects of olfactory ensheathing cell transplantation on functional recovery of rats with complete spinal cord transection.

Data Sources: A computer-based online search of Medline (1989-2013), Embase (1989-2013), Cochrane library (1989-2013), Chinese Biomedical Literature Database (1989-2013), China National Knowledge Infrastructure (1989-2013), VIP (1989-2013), Wanfang databases (1989-2013) and Chinese Clinical Trial Register was conducted to collect randomized controlled trial data regarding olfactory ensheathing cell transplantation for the treatment of complete spinal cord transection in rats.

Selection Criteria: Randomized controlled trials investigating olfactory ensheathing cell transplantation and other transplantation methods for promoting neurological functional recovery of rats with complete spinal cord transection were included in the analysis.

Tranexamic acid reduces postoperative blood loss of degenerative lumbar instability with stenosis in posterior approach lumbar surgery: a randomized controlled trial.

Study Design: This study is randomized controlled trial.

Purpose: To evaluate the effect of tranexamic acid (TXA) on reducing postoperative blood loss in posterior approach lumbar surgery for degenerative lumbar instability with stenosis.

Methods: Sixty patients with degenerative lumbar instability with stenosis were randomized into TXA and control groups, receiving 15 mg/kg body weight of TXA or placebo (0.