Publications by authors named "Meihuan Ji"
Article Synopsis
- The study developed heterojunctions of CuInS embedded in g-CN for effective activation of peroxymonosulfate (PMS) under visible light to degrade levofloxacin (LVF).
- Characterization methods such as XRD, FTIR, SEM, and TEM were used to confirm that the created composites reduce the recombination of photogenerated electron-hole pairs.
- The 3CIS/GCN variant showed over 98.9% efficiency in degrading LVF in 60 minutes across various pH levels, with a strong emphasis on the roles of reactive species and minimal metal leaching, indicating its potential for degrading hazardous pollutants.
Histone post-translational modifications (PTMs) on lysine residues, including methylation, ubiquitylation, and sumoylation, have been studied using semisynthetic histones reconstituted into nucleosomes. These studies have revealed the in vitro effects of histone PTMs on chromatin structure, gene transcription, and biochemical crosstalk. However, the dynamic and transient nature of most enzyme-chromatin interactions poses a challenge toward identifying specific enzyme-substrate interactions.
View Article and Find Full Text PDFAn efficient total chemical synthesis of site-specifically sumoylated histone H4 was undertaken to generate homogenously modified mononucleosomes. These were tested as substrates in biochemical assays with the histone H2B-specific ubiquitin ligases Rad6 and Bre1, which revealed the strong inhibition of H2B ubiquitylation by SUMO. This novel negative biochemical crosstalk between SUMO and ubiquitin was also confirmed to exist in human cells.
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