A single-center's uric acid profile in girls with Turner syndrome.

Background: Metabolic disorders are common in individuals with Turner syndrome (TS). Hyperuricemia is associated with metabolic syndrome. This study investigated the serum uric acid (SUA) profile in patients with TS.

Expression and immunogenicity of non-structural protein 8 of porcine epidemic diarrhea virus.

The non-structural protein (nsp) 8 of the porcine epidemic diarrhea virus (PEDV) is highly stable across different PEDV strains and plays an important role in PEDV virulence. In current study, nsp8 prokaryotic expression vectors were constructed based on parental vectors pMAL-c2x-maltose binding protein (MBP) and pET-28a (+). Subsequently, the optimization of expression conditions in , including induced temperature, time and isopropyl β-D-thiogalactopyranoside concentration were performed to obtain a stable expression of MBP-nsp8 and nsp8.

plays oncogenic role in hepatocellular carcinoma progression through suppressing expression and activating PI3K/AKT pathway.

Given their regulatory roles in gene expression, microRNAs play an important role in tumorigenesis. The current study aimed to explore the function and the related mechanisms of in hepatocellular carcinoma (HCC). The expression of was detected using quantitative real-time polymerase chain reaction (qRT-PCR).

The impact of APC polymorphisms on the transition from polyps to colorectal cancer (CRC).

Objective: The purpose of this study was to investigate the function of APC polymorphisms (D1822V and E1317Q) on the transition from polyps to colorectal cancer (CRC).

Methods: 259 patients with polyps were included in the study. APC polymorphisms were genotyped via polymerase chain reaction (PCR) and subsequent sequencing.