Combined application of MRS and DWI can effectively predict cell proliferation and assess the grade of glioma: A prospective study.

In order to assess combined application of MRS and DWI for prediction cell proliferation and grade diagnosis of glioma, We prospectively collected the Cho/Cr, Cho/NAA, Cr/NAA of MRS and tumor parenchyma ADC (ADC), contralateral mirror brain tissue ADC (ADC), rADC (rADC = ADC/ADC). According to postoperative pathology, the patients were divided into two groups: LGG group and HGG group, compared differences of age, gender, Ki67, MRS, DWI between two groups. Next, we analyzed the correlation between MRS, DWI and Ki67.