An effective method for controlling the corrosion rate of Mg-based implants must be urgently developed to meet the requirements of clinical applications. As a naturally occurring osteoid material, nacre offers a strategy to endow biomedical Mg alloys with excellent biocompatibility, and corrosion resistance. In this study, pearl powder and NaH2PO4 were used as precursors to deposit coatings on AZ91D alloy substrates hydrothermally based on Na2EDTA-assisted induction.
View Article and Find Full Text PDFThe effects of molecular structures of the compatibilizers and blending sequences on the morphology and properties of the immiscible poly(l-lactide)/acrylonitrile-butadiene-styrene (PLLA/ABS) blend are investigated herein. The comb-like polymers (RC), which are constituted by a poly(methyl methacrylate) (PMMA) backbone and side chains and a few epoxy groups distributed randomly along the backbone, are found to be better compatibilizers for improving the morphology and mechanical properties of the PLLA/ABS blend, compared to linear polymers (RL) constituted by a PMMA backbone and epoxy groups along the backbone. In addition, the blending sequence, which dictates the extent of grafting reaction between carboxyl end groups of PLLA and epoxy groups in the RL and RC compatibilizers, is found to influence the diffusion and location of the formed RL--PLLA and RC--PLLA polymers in the blend system.
View Article and Find Full Text PDFBackground: This meta-analysis was conducted to evaluate the diagnostic value of near-infrared (NIR) or fluorescent indocyanine green (ICG) guided sentinel lymph node (SLN) mapping in gastric cancer (GC).
Methods: This meta-analysis was registered at the PROSPERO. Clinical studies were retrieved from the electronic database Pubmed, Embase, Medline, Web of science, and the Cochrane Library.
Unlabelled: Nanoscale drug depots, comprising a drug reservoir surrounded by a carrier membrane, are much sought after in contemporary pharmaceutical research. Using cellulose acetate (CA) as a filament-forming polymeric matrix and ferulic acid (FA) as a model drug, nanoscale drug depots in the form of core-shell fibers were designed and fabricated using a modified tri-axial electrospinning process. This employed a solvent mixture as the outer working fluid, as a result of which a robust and continuous preparation process could be achieved.
View Article and Find Full Text PDFAim: To discuss the effects of different concentrations of tetramethylpyrazine (TMP), an active constituent of Chinese herb, on damaged Shandong human corneal epithelial cell (SDHCEC) induced by hydrogen peroxide.
Methods: We detected the combined effects of TMP with concentrations ranging from 4 mg/mL to 0.03 mg/mL and 800 µM hydrogen peroxide on SDHCEC.
Background: Dry eye (DE) is a common eye disease, and appropriate animal models are essential to explore the pathogenesis and therapy of DE. In this study, we aimed to establish rabbit models by three methods.
Methods: In group A, the lacrimal gland, Harderian gland, and nictitating membrane of the left eyes were surgically removed.
Int J Ophthalmol
August 2012
Aim: To determine the value of Schirmer I test (S I t) without anesthesia and with topical anesthesia for diagnosing dry eye (DE).
Methods: Totally 220 eyes in 110 patients, male (44) and female (66), (39.56±12.
The aim of this study was to investigate the electrochemical behavior of Co-Cr alloy in artificial saliva containing (-)-epigallocatechin gallate (EGCG) and to characterize the composition and structure of the passive film formed by potentiodynamic polarization.Electrochemical measurements ranked the corrosion resistance of Co-Cr dental cast alloy as follows when exposed to artificial saliva containing different concentrations of EGCG: 4.0 g/L<2.
View Article and Find Full Text PDFTetramethylpyrazine (TMP), extracted from the Chinese herbal medicine Ligusticum wallichii franchat (chuan xiong in Chinese), is a potent anti-free radical and calcium antagonist. Correspondingly, two important hypotheses in the causation of cataracts are free radical toxicity and calcium ion overload. In this study we investigated the effect of TMP on lens opacification induced by sodium selenite in rats, addressing the potential of TMP eye drops to prevent and treat cataracts.
View Article and Find Full Text PDFPurpose: To study the aqueous humor penetration of ligustrazine hydrochloride after ocular administration in rabbits.
Methods: Eighteen rabbits were randomly divided into 6 groups. The aqueous humor was collected at 5, 15, 30, 60, 120 and 180 minutes following topical administration of ligustrazine hydrochloride eye drops and the concentration of ligustrazine hydrochloride was determined by HPLC.
Objective: To study the cytotoxic effects of three kinds of eye drops on human cancer cells and normal cells.
Methods: Cytotoxic effects of Yuxingcao Eye Drop (YXC), Gegensu Eye Drop (GGS) and Shuanghuanglian Eye Drop (SHL) on 6 cell lines (CNE2, Glc-82, HRPE, Fibro, 3T3 and ECV-304) were assayed using MTF method. And cytotoxic efficacy was evaluated using fifty percent of inhibitory concentration (IC50).