Combination of fractional carbon dioxide laser with recombinant human collagen in periocular skin rejuvenation.

Background: The most visible sign of facial aging is often seen in the periocular area. However, periocular rejuvenation remains challenging due to the particularity of periocular anatomic locations.

Aims: We aimed to evaluate the efficacy and safety of the fractional-ablative CO laser-facilitated recombinant human collagen permeation in periocular rejuvenation.

Dietary fatty acids and risk for Alzheimer's disease, dementia, and mild cognitive impairment: A prospective cohort meta-analysis.

The association between dietary fatty acid intake and Alzheimer's disease (AD), dementia, and mild cognitive impairment (MCI) risk is inconsistent. This meta-analysis examined the effect of dietary fatty acid intake in prospective cohort studies including patients with AD, dementia, and MCI. PubMed, China Biology Medicine (CBM), China National Knowledge Infrastructure (CNKI), Wanfang Data, and VIP Database were systematically searched through September 2020.

[Effects of Restraint Manipulation on Learning-memory Ability, Visional Acuity and Body Mass of Rats].

Objective: Restraint manipulation is necessary for observing the effect of acupuncture or moxibustion stimulation on various variables in the experimental study. Thus, the present study was designed to examine the impact of restraint manipulation on rats' learning-memory ability, visional acuity, and body mass, so as to have a reasonable assessment on the influence of restraint stress.

Methods: Normal Sprague Dawley rats were randomly assigned to a restraint group (=15) and a control group (=15).

Different patterns of changes between actin dynamics and synaptic density in the rat's primary visual cortex during a special period of visual development.

In our previous study, we found that the normalized levels of the synaptosomal filament actin (F-actin) to monomeric global actin (G-actin) ratio in the primary visual cortex (V1) of rats was significantly lower on postnatal day (P) 45 compared with P30, however, the synaptic density in the monocular area of primary visual cortex (V1M) maintained a stable high level from P30 to P45. The mechanisms underlying the different patterned of change in synaptic density and actin rearrangements from P30 to P45 are unclear. During visual development, there is a synaptic pruning process in the binocular segment of primates' visual cortex (V1B) and we suppose the pruning activity may contribute to the decreased synaptosomal F-actin to G-actin ratio.

GABA and GABA receptors alterations in the primary visual cortex of concave lens-induced myopic model.

Until recently most researches on myopia mechanisms have mainly been focused on the eye ball and few investigations were explored on the upper visual pathway, such as the visual cortex. The roles of gamma-aminobutyric acid (GABA) in the retinal and in the upper visual pathway are inter-correlated. As the retinal glutamate decarboxylase (GAD), GABA, and the mRNA levels of GABA receptors increased during the concave lens induced myopia formation, however, whether GABA alterations also occurred in the visual cortex during the concave lens induction is still unknown.

[Early multi-disciplinary intervention reduces neurological disability in premature infants].

Objective: This study aimed to evaluate the effectiveness of multi-disciplinary treatment approaches in reducing neurological disabilities in premature infants.

Methods: A total of 117 infants who were born premature in our hospital between March 2008 and February 2010 but had no congenital malformations and no severe neonatal complications, were enrolled in this study. They were randomly allocated to a multi-disciplinary treatment group (n=63) and a control group (n=54).

[Microscopic Raman spectral characteristics and diagnostic value of pathological lip minor salivary glands affected in primary Sjögren's syndrome].

Objective: To investigate the Raman spectral characteristics of the pathological lip minor salivary glands affected in primary Sjögren's syndrome.

Methods: Thirty pathological samples and 30 normal samples were collected in this study. The samples were examined by Raman microscope.