[The protective effect of puerarin on Abeta(25-35)-induced PC12 cell injury].

Objective: To study The protective effect of puerarin on Abeta(25-35)-induced PC12 cell injury.

Methods: PC12 cells were treated with puerarin for 0.5 h, then incubated with Abeta(25-35) (50 micromol/L) for 24 h to investigate the production of reactive oxygen species (ROS), mitochondrial membrane potential levels and Caspase-3 activation; The expressions of Bax, bcl-2 were measured by Western Blotting.