Acute major gastrointestinal bleeding caused by hookworm infection in a patient on warfarin therapy: A case report.

Rationale: The use of anticoagulants is a contributor to gastrointestinal (GI) bleeding. Most bleeding patients on anticoagulant therapy such as warfarin commonly have basic lesions existing in their GI mucosa.

Patient Concerns: We report a case of major GI bleeding following the use of anticoagulants in a patient with hookworm infection.

Functional and structural alterations of peritoneum and secretion of fibrotic cytokines in rats caused by high glucose peritoneal dialysis solutions.

Objective: To determine functional and structural alterations of peritoneum and fibrotic cytokines expression in peritoneal dialysis (PD) rats.

Methods: 28 Sprague-Dawley (S-D) rats were randomly divided into four groups and dialyzed with various solutions daily for four weeks: (1) no solution (CON group), (2) 0.9% Saline solution (NS group), (3) 1.

Enhancing effect of ultrasound-mediated microbubble destruction on gene delivery into rat kidney via different administration routes.

Objective: To investigate the efficiency of β-galactosidase gene transfer into rat kidney with ultrasound-mediated microbubble destruction via different injection routes.

Methods: A total of 25 Wistar rats were randomly divided into 5 groups. Four groups received a mixture of optison microbubbles (0.

[Transperitoneal transport of solute and IL-8 in dialysis-related peritonitis].

Objective: To study the changes in solute transperitoneal transport and the IL-8 level at different time phases in dialysis-related peritonitis so as to understand the mechanism of solute transperitoneal transport.

Methods: Forty-two New Zealand white rabbits were randomly divided into three experimental groups (5 min, 24 h, and 48 h groups) and a control group. The rabbit model of peritoneal dialysis-related peritonitis was created.