Publications by authors named "Mei-Zhen Chen"
Article Synopsis
- Milk fat globule membrane (MFGM) is important for infant development but is not present in standard infant formulas; this study aimed to assess the safety of adding MFGM to formula for infants aged 0 to 12 months.
- In a trial involving 375 infants, those on MFGM-enriched formula experienced fewer instances of diarrhea and soft stools compared to those on standard formula, indicating better digestive tolerance.
- Overall, MFGM-enriched formula was found to be safe and well-tolerated, although breast-fed infants showed better growth and health outcomes compared to both formula-fed groups.
Hepcidin, a member of cysteine-rich antimicrobial peptides, plays an important role in both fish adaptive immunity and the regulation of iron metabolism. In this paper, the nucleotide sequence of a full-length cDNA clone for ayu (Plecoglossus altivelis) hepcidin gene, 763 nucleotides in length, was determined. Ayu hepcidin gene contained a complete open reading frame (ORF) encoding an 85-amino-acid peptide with a molecular weight of 9.
View Article and Find Full Text PDFIn this paper, in vitro anti-influenza virus activities of sulfated polysaccharide fractions from Gracilaria lemaneiformis were investigated. Cytotoxicities and antiviral activities of Gracilaria lemaneiformis polysaccharides (PGL), Gracilaria lemaneiformis polysaccharide fraction-1 (GL-1), Gracilaria lemaneiformis polysaccharide fraction-2 (GL-2) and Gracilaria lemaneiformis polysaccharide fraction-3 (GL-3) were studied by the Methyl thiazolyl tetrazolium (MTT) method, and the inhibitory effect against Human influenza virus H1-364 induced cytopathic effect (CPE) on MDCK cells were observed by the CPE method. In addition, the antiviral mechanism of PGL was explored by Plaque forming unit (PFU), MTT and CPE methods.
View Article and Find Full Text PDFProduction of a human single-chain variable fragment antibody against esophageal carcinoma.
World J Gastroenterol
September 2004
Aim: To construct a phage display library of human single-chain variable fragment (scFv) antibodies associated with esophageal cancer and to preliminarily screen a scFv antibody against esophageal cancer.
Methods: Total RNA extracted from metastatic lymph nodes of esophageal cancer patients was used to construct a scFv gene library. Rescued by M13K07 helper phage, the scFv phage display library was constructed.