Effect of blockage of Trem1 on the M1 polarization of macrophages in the regulation dental pulp inflammation.

Dental pulp inflammation is a common and significant factor related to poor dental prognosis. Current treatment strategies primarily concentrate on managing the inflammatory response, with specific targets for intervention still under investigation. Triggering receptors expressed on myeloid cells (TREMs) are a group of receptor molecules extensively present on myeloid cell surfaces, crucial in the regulation of inflammatory process.

A new dipeptide isolated from the bulb of garlic.

(R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid was isolated from the bulb of garlic, together with four known amino acids. Its structure was elucidated on the basis of 2D NMR and MS techniques. To the best of our knowledge, (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid, which showed antibacterial activity against the Staphylococcus aureus antibiotic resistant strain, was the first example of dipeptide from garlic.

N-(2-Bromo-phen-yl)-1,3-selenazolo[5,4-b]pyridin-2-amine.

The mol-ecular structure of the title mol-ecule, C12H8BrN3Se, is built up from fused selenazolo and pyridine rings, linked to a 2-bromo-aniline group. In the crystal, pairs of mol-ecules are linked by N-H⋯N hydrogen bonds into dimers, forming eight-membered ring motifs.

1,2-Bis(4-methyl-benz-yl)diselane.

The title mol-ecule, C(16)H(18)Se(2), features a diselenide bridge between two 4-methyl-benzyl units, in which the central C-Se-Se-C torsion angle is 88.1 (3)°, while the two Se-Se-C-C fragments assume gauche conformations, with torsion angles of -51.8 (5) and 59.

Bis(2,6-dichloro-benz-yl)selane.

The title mol-ecule, C(14)H(10)Cl(4)Se, features a selenide bridge between two dichloro-benzyl units. The dihedral angle between the two benzene rings is 107.9 (16)°.

1-{2-[(2-hydroxybenzylidene)-amino]-ethyl}-3-methyl-3H-imidazolium hexafluorophosphate.

The title Schiff base compound, C(13)H(16)N(3)O(+)·PF(6) (-), was derived from the condensation of 2-hydroxy-benaldehyde with the ionic liquid 1-(2-amino-ethyl)-3-methyl-imidazolium hexa-fluoro-phosphate in an ethanol solution. The asymmetric unit comprises one cation and two PF(6) (-) anions. The dihedral angle between the aromatic and imidazole rings is 15.

[Effects of Xuanyinning Recipe on invasion of SPC-A-1 cells and pathomorphological changes of peritoneum in mice inoculated with sarcoma 180].

Objective: To observe the effects of Xuanyinning Recipe (XYNR) in inhibiting SPC-A-1 cellular infiltration and on the pathomorphological changes of peritoneum in mice inoculated with sarcoma 180 (S(180)).

Methods: On the bases of isolated culture of mouse peritoneal mesothelial cells, we adjusted and added the human lung adenocarcinoma cell line SPC-A-1 into the double-layer culture medium to observe the number of clones formed. We also took out the peritoneum from the mice administered with three different dosages of XYNR and observed its pathomorphological changes with transmission electron microscope.

A quantitive evaluation of gap junctions and their morphological alteration during differentiation of amphibian notochord cells.

The early development of notochord cells may be divided into three phases according to the quantitative evaluation of gap junctions: late gastrula, neurula and from tailbud to tadpole. In late gastrula, the percentage of the area of gap junctions to total membrane is 0.054% and most of the gap junctions are small in size.