Quality assessment of variable collagen tissues of sea cucumber (Stichopus japonicus) body wall under different heat treatment durations by label-Free proteomics analysis.

The microstructure of the body wall, body wall composition, and collagen fibers of sea cucumber (Stichopus japonicus) under different heating times (1 h, 4 h, 12 h, and 24 h) was investigated based on heat treatment at 80 °C. A Label-Free proteomics technique was applied to study the proteomic changes in the body wall of sea cucumbers under 4 and 12 h of heat treatment. Compared with the fresh group, 981 proteins were found to be differentially expressed proteins (DEPs) after heat treatment at 80 °C (4 h), and 1110 DEPs were observed after heat treatment at the same temperature for 12 h.

Metabolic profiling of lysophosphatidylcholines in chlorpromazine hydrochloride- and -acetyl--amino-phenoltriptolide-induced liver injured rats based on ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry.

Chlorpromazine hydrochloride (CH) and -acetyl--amino-phenoltriptolide (APAP) are typical acentral dopamine receptor antagonists and antipyretic analgesics in clinical applications, respectively. However, it has been reported that these 2 drugs could cause liver damage. Lysophosphatidylcholines (LPCs) have multiple physiological functions and are metabolized primarily in the liver, where it undergoes significant changes when the liver is damaged.

[Effect of medicated bath plus acupoint massage on limbs in treating 42 patients with diabetic peripheral neuropathy].

Objective: To observe the effect of medicated bath plus acupoint massage on limbs (B-M treatment) in treating diabetic peripheral neuropathy (DPN).

Methods: Eighty-two patients were divided into two groups, the control group (n=40) and the treated group (n=42), they were treated by conventional treatment but with B-M treatment applied to the latter additionally, the course to both groups was 12 weeks. The curative effects obtained were compared after treatment.