DNA separation with low-viscosity sieving matrix on microfabricated polycarbonate microfluidic chips.

Microfluidic devices have been fabricated on polycarbonate (PC) substrates by use of a hot embossing method using a silicon master template. By adding auxiliary lines around the functional channel on the silicon master, its lifetime was significantly prolonged and the bonding strength of the PC cover plate to the microfluidic chip was greatly improved. More than 300 polycarbonate microfluidic chips have been replicated with the same silicon mold.

[Progress in techniques of interfacing capillary electrophoresis with inductively coupled plasma mass spectrometry].

The coupling of capillary electrophoresis (CE) with inductively coupled plasma mass spectrometry (ICP-MS) has demonstrated multiple advantages, including high separation efficiency, sensitivity and resolution, as well as low sample consumption and detection limit. The technique has been widely used for the speciation of environmental and biological samples. The interface between CE and the nebulizing system of ICP-MS plays a key role in the hyphenation of CE and ICP-MS.