Publications by authors named "Mei-Xin He"

Background And Objective: This study comprehensively evaluates the distribution patterns and antimicrobial resistance profiles of urinary pathogens in Preoperative midstream urine cultures collected from patients with urinary calculi in China over the last two decades.

Methods: A cross-sectional analysis of 41 studies was conducted. A systematic search across various databases, including Wanfang Data, CNKI, SinoMed, Embase, PubMed, and Web of Science, was carried out, covering the time period from 2002 to 2022.

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Based on the monitoring data of five pollutants in 168 key cities under air pollution prevention and control in China from 2015 to 2020, using the MAKESENS model and the aggregate risk index(ARI), this study quantitatively analyzed the spatial and temporal distribution characteristics of air pollution and health risks in China and the six urban agglomerations. The results showed that:① PM pollution was the most serious pollution in Chinese key cities. Only 15% of the cities' six-year average concentrations of PM reached the National Secondary Standard, followed by that of NO; 77% of the cities' six-year average concentrations of NO reached the National Secondary Standard.

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Routine examination for intraoperative histopathologic assessment is lengthy and laborious. Here, we present the dark-field reflectance ultraviolet microscopy (DRUM) that enables label-free imaging of unprocessed and thick tissues with subcellular resolution and a high signal-to-background ratio. To the best of our knowledge, DRUM provides image results for pathological assessment with the shortest turnaround time (2-3 min in total from sample preparation to tissue imaging).

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Fine particulate matter (PM) exposure has been linked to numerous adverse health effects, with some disadvantaged subgroups bearing a disproportionate exposure burden. Few studies have been conducted to estimate the exposure and inequality of different subgroups due to a lack of adequate characterization of disparities in exposure to air pollutants in urban areas, and a mechanistic understanding of the causes of these exposure inequalities. Based on a long-term series of PM concentrations, this study analyzed the spatial and temporal characteristics of PM in 31 provincial capital cities of China from 2000 to 2016 using the coefficient of variation and trend analyses.

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Background: Talaromyces marneffei, formerly known as Penicillium marneffei, is a significant emerging pathogenic fungus in Southeast Asia which can generate life-threatening systemic infections. Human immunodeficiency virus (HIV) infection is considered as the most underlying disease among systemic infections. However, infections due to T.

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Background: Intervertebral disc degeneration (IDD) was considered to be the pathological basis of intervertebral disc herniation (IDH). However, the plasma melatonin in the IDD cases and healthy controls remained unclear.

Methods: In this case-control study, a total of 71 IDD cases and 54 healthy controls were enrolled between April 2020 and August 2020.

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Article Synopsis
  • A 56-year-old male presented with chromoblastomycosis, characterized by large plaque and verrucous hyperplasia on his left upper limb and elbow abnormalities.
  • Diagnosis was confirmed through gross and microscopic assessments, along with the identification of the causative agent, Fonsecaea nubica, using molecular tools.
  • The patient successfully underwent a treatment regimen that included oral antifungals and thermotherapy, and a review of similar cases highlighted that other patients were also males over 30, with lesions following trauma.
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Previous studies have demonstrated that miR-486-5p functions as a tumor suppressor or oncogene in various types of cancer. In the present study, we showed that miR-486-5p was significantly down-regulated in papillary thyroid carcinoma (PTC) tissues and cell lines, whereas miR-486-5p down-regulation inhibited PTC cell proliferation and increased apoptosis. Conversely, under-expression of miR-486-5p enhanced PTC cell proliferation and decreased apoptosis.

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