Publications by authors named "Mei-Xiao Li"
Article Synopsis
- The modified Xiaoyao San (MXS) is a traditional Chinese medicine recommended for liver cancer treatment, showing promise in preventing the recurrence of hepatocellular carcinoma and enhancing survival rates.
- MXS was tested on a rat model of nonalcoholic steatohepatitis (NASH), revealing its ability to reduce lipid accumulation and inflammation while activating the AMPK pathway and suppressing key regulators associated with liver disease progression.
- The research identified that MXS positively impacts arachidonic acid metabolism and steroid hormone synthesis, especially by inhibiting male hormone metabolism, suggesting its potential as a therapeutic agent for liver-related conditions.
Article Synopsis
- The study looked at how well a special scan (F-PSMA-1007 PET/CT) can predict how serious prostate cancer is based on a grading system called Gleason.
- Researchers tested 53 patients and found that certain measurements from the scans were really good at telling apart high-grade cancer (more serious) from low-grade cancer (less serious).
- The key findings were that two specific scan measurements (iPSMA-TV and iTL-PSMA) were the best at predicting the cancer grade and could help doctors understand how to treat it better.
The aim of this paper was to investigate the immunosuppressive effects of dihydroartemisinin and Huobahua compatibility in mice with delayed hypersensitivity and explore its possible mechanism. The delayed-type hypersensitivity(DTH) model in mice was established to observe the immunosuppressive effects of dihydroartemisinin and Huobahua compatibility in DTH mice. ELISA assay was used to detect the contents of interferon(IFN-γ); histopathological changes and degree of mononuclear infiltration of right ear tissues were examined by HE staining; the expression level of intercellular cell adhesion molecule-1(ICAM-1) in the right ear of mice was detected by immunohistochemistry; the protein expression levels of p38 phospho mitogen activated protein kinase(p-p38 MAPK) was detected by Western blot analysis.
View Article and Find Full Text PDFHand, foot, and mouth disease (HFMD) spreads rapidly and has been recognized as a public health problem in recent years in China. Unfortunately, there is no effective vaccine or antiviral drug currently for EV71 infection. In this study, we aim to identify biomarker which are associated with for severity of EV71 infection cases using high-throughput RNA sequencing approach.
View Article and Find Full Text PDF[Changes of mean platelet volume, fibrinogen content and blood rheology in peripheral blood of youth patients with cerebral infarction].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2012
This study was aimed to explore the correlation of mean platelet volume (MPV), fibrinogen (FIB) and blood rheology with the youth patients with cerebral infarction, so as to provide the basis for the clinical early diagnosis and treatment. The 109 patients with cerebral infarction aged between 18 - 45 were divided into three group: the large (> 10 cm(3)), middle (4 - 10 cm(3)) and small (< 4 cm(3)) area infarction; 30 healthy persons were served as control group. All the four groups were subjected to 16 examinations, such as MPV, FIB, and rheology (Lηb, Mηb, Hηb, ηp, Lηr, Mηr, Hηr, KVE, EAI, ERI, EDI, EEI, HCT, ESR).
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